Journal of Isfahan Medical School

Journal of Isfahan Medical School

Comparison of Three Methods of Open Discectomy, and Nucleoplasty with and without Ozone Injection on the Healing, Complications, and Postoperative Pain in Patients with Lumbar Disc Herniation

Document Type : Original Article (s)

Authors
Saeed Abrishamkar 1
Amin Rastgoo 2
Marjan Ostad 3
Ehsan Mohamadhoseini 2
Mohamad Kamangar 2
1 Professor, Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Resident Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Resident, Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
10.22122/jims.v36i485.9960
Abstract
Background: This study aimed to compare the effect of three method of open discectomy, and nucleoplasty with and without ozone injection on the healing, complications, and postoperative pain in patients with lumbar disc herniation.Methods: In this clinical trial study, 180 patients with intervertebral disc herniation were divided into three groups of 60 patients. The first group was operated using open diskectomy method, and the second and third groups were operated with nucleoplasty with and without ozone injection. The severity of pain, relapse symptoms, and postoperative complications were followed up to 24 months later, and compared between the three groups.Findings: The severity of back pain at preoperative, 14 days, and 1 and 3 months after operation was not significantly different between the three groups; but 24 months after surgery, patients with open discectomy had lower pain severity (P = 0.029). Up to 24 months later, 12 patients needed re-operation, 2 (3.3%) of nucleoplasty with ozone injection group and 10 (16.7%) of the nucleoplasty without ozone injection group, and the difference between the three groups was significant (P = 0.001).Conclusion: It seems that the use of open discectomy method, in comparison with nucleoplasty with or without gas injection, is associated with a higher rate of cure and a less recurrence rate; although open discectomy is not accompanied by a getting rid of bed quickly, but had less therapeutic costs and less need for reoperation.
Keywords
Diskectomy
Ozone
Low back pain
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Journal of Isfahan Medical School
Volume 36, Issue 485 - Serial Number 485
May and June 2018
Pages 705-711

  • Receive Date 19 April 2018
  • Accept Date 06 April 2022