Journal of Isfahan Medical School

Journal of Isfahan Medical School

Comparing the Effect of Aromatherapy with Lavender and Rose Essential Oils on the Prevention of Headache Induced by Infusion of Nitroglycerin in Cardiac Care Unit

Document Type : Original Article (s)

Authors
Maryam Moradi 1
Fereshteh Jalili 2
Mahdi Basiri-Moghadam 3
Kokab Basiri-Moghadam 4
1 Nursing Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
2 MSc of Nursing, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran
3 Faculty Member of Nursing, School Nursing, Gonabad University of Medical Sciences, Gonabad, Iran
4 Assistant Professor, Department of Surgery Technology, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran
10.48305/jims.v40.i670.0300
Abstract
Background: Headaches are a side effect of nitrates that limits the use of this drug in some patients. The aim of this study was to determine the effect of aromatherapy and lavender essential oils on the prevention of headache induced by infusion of Nitroglycerin in cardiac care units.
Methods: In this randomized clinical trial, 45 patients with heart disease were selected by convenience sampling and randomly assigned into 3 groups. In the intervention groups (roses and lavender), as soon as the infusion of nitroglycerin was started, cotton submerged in 3 drops of the essential oil was inhaled for half an hour and no aromatherapy was used in the control group. The frequency of headache was measured by using visual analogue scale at 90 minutes after aromatherapy. In case of headache in any of the groups, usual treatment of headache, acetaminophen tablet 325 mg, was used. This was also recorded in the patient's checklist. Data were analyzed by SPSS at the significant level of 0.05.
Findings: The frequency of headache during the study period was not statistically significant in the three groups. However, the amount of acetaminophen used to relieve headache in the rose group was less than the control and lavender groups significantly.
Conclusion: Aromatherapy with rose and lavender essential oils may reduce the headache caused by infused nitroglycerin. Therefore, it is recommended to be considered as one of the effective treatments.
Keywords
Aromatherapy
Headache
Nitroglycerin
lavender
Rose
  1. Sedighi M, Cheraghi M, Hashemzadeh P. A review of related risk factors in diabetic patients and the chance of involvement in cardiovascular diseases [In Persian]. Yafte 2021; 23(0): 220-36.
  2. Smeltzer SC, Bare BG, Hinkle JL, Cheever KH. Brunner and Suddarth’s Text book of medical-surgical nursing. 12th Philadelphia, PA: Lippincott Williams & Wilkins; 2010.
  3. Hosseini S, Karamizadeh R, Sadeghi T, Esmaeili A. The effect of nitroglycerin spray and pearl on pain intensity and physiological indices of people with chest pain [In Persian]. Cardiovasc Nurs J 2017; 6(3): 48-55.
  4. Heidari R, Sadeghi M, Sanei H, Rabie K. The effect of trinitroglycerine injection on angiographic complications [In Persian]. Journal of Inflammatory Diseases 2010; 14(3): 5-10.
  5. Modares M, Rahnama P. Side effects of glyceryl trinitrate ointment for primary dysmenorrhea: a randomized clinical trial [In Persian]. Tehran Univ Med J 2008; 65(10): 61-66.
  6. Yadollahi P, Taghizdeh Z, Ebadi A, Khormaei F. Development and validation of the perception of labor pain questionnaire among Iranian women. Int J Community Based Nurs Midwifery 2019; 7(2): 128-37.
  7. Zarifnejad G, Eshghi E, Mirhaghi A, ghorbanzadeh H. The effect of aromatherapy with Lavender essential oil in treatment of headache due to Nitroglycerine infusion in patient admitted to cardiac emergency department [In Persian]. Complement Med J 2015; 16(3): 1248-57.
  8. Mirmohamad Aliei M, Khazaie F, Rahnama P, Rahimikian F, Modarres M, Bekhradi R, et al. Effect of Lavender on Pain during Insertion of Intrauterine Device: A Clinical Trial. [In Persian]. J Babol Univ Med Sci 2013; 15(4): 93-9.
  9. Moradi M, Mohammadzadeh H, Noori R, Basiri Moghadam K, Sadeghmoghadam L. Effect of a sleep hygiene education program using telephone follow-up method on the sleep quality of the elderly [In Persian]. Salmand: Iranian Journal of Ageing 2021; 15(4): 484-95.
  10. Rahgoi A, Mohammadzadeh Zarankesh S,
    Kasaeizadeghan SS, Naghibeiranvand M. Effect of classical music on physiological characteristics and observational and behavioral measures of pain in unconscious patients admitted to intensive care units [In Persian]. Complement Med J 2021; 10(4): 368-79.
  11. Jafarbegloo E, Ahmari Tehran H, Bakouei S. The impacts of inhalation aromatherapy with lavender essential oil on students’ test anxiety: a randomized placebo-controlled clinical trial [In Persian]. Journal of Medicinal Plants 2020; 19(73): 100-8.
  12. Mirjalili M ZA, Mirhosseini A, Arabzadeh M. To determine the chemical composition and properties of lavender Medicinal herbs (Lavandula Officinalis). Proceedings of the National Conference on Natural Products and Medicinal Plants 2013; 1(1).
  13. Davari M, Reihani M, Khoshrang N. The aromatherapy effect of rosemary and lavander on primary dysmenorrhea: a clinical controlled trial [In Persian]. J Isfahan Med Sch 2014; 32(290): 1-9.
  14. Anbari S, Estaji Z, Rastaqhi S. Assessment effect of rosa damascena juice aromatherapy on elderly chronic musculoskeletal pain in sabzevar retirement clubs [In Persian]. Salmand: Iranian Journal of Ageing 2018; 13(2): 250-61.
  15. Boskabady MH, Shafei MN, Saberi Z, Amini S. Pharmacological effects of Rosa damascena. Iranian J Basic Med Sci 2011; 14(4): 295-307.
  16. Latthe P, Latthe M, Say L, Gülmezoglu M, Khan KS. WHO systematic review of prevalence of chronic pelvic pain: a neglected reproductive health morbidity. BMC Public Health 2006; 6(1): 177.
  17. Farooq Danish K, Rashid Chaudhry A, Khan SS. Intractable headache as a side effect of topical nitroglycerin ointment. RMJ 2008; 33(1): 15-7.
  18. Hsi DH, Roshandel A, Singh N, Szombathy T, Meszaros ZS. Headache response to glyceryl trinitrate in patients with and without obstructive coronary artery disease. Heart 2005; 91(9): 1164-6.
  19. Noike H, Iizuka T, Matsumoto J, Kaku M, Yoshinaga K, Aoyagi K, et al. Headache due to nitroglycerin administration and its clinical significance. J Cardiol 2002; 40(4): 159-65.
Journal of Isfahan Medical School
Volume 40, Issue 670
2nd Week, July
July and August 2022
Pages 300-360

  • Receive Date 10 January 2022
  • Accept Date 29 May 2022