Journal of Isfahan Medical School

Journal of Isfahan Medical School

Protective Effect of Aerobic Training and Spirulina on Ghrelin and Obestatin in Overweight Elderly Men

Document Type : Original Article (s)

Authors
Mostafa Babaei 1
Ahmad Abdi 2
Asieh Abbassi Daloii 2
Javad Mehrabani 3
1 PhD Student, Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2 Associate Professor, Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
3 Associate Professor, Department of Exercise Physiology, School of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran
10.48305/jims.v40.i679.0509
Abstract
Background: The prevalence of obesity in the elderly has increased dramatically in recent years. Therapeutic strategies that can help maintain energy homeostasis in old age are of great importance. The aim of this study was to investigate the protective effect of aerobic training and spirulina on ghrelin and obestatin in overweight elderly men.
Methods: In this experimental study, 36 obese adult men from Anzali were selected and randomly divided into four groups: control, spirulina, exercise and exercise-spirulina. The supplement groups received 2 tablets (500 mg) daily in the morning and evening during the intervention period. Exercise groups performed 3 sessions of aerobic exercise on a treadmill each week with an intensity 70-85% of maximum heart rate for eight weeks. Serum ghrelin and obestatin levels were measured by ELISA kit. Data were analyzed using paired t-test, analysis of covariance and Bonferroni post hoc test.
Findings: The results showed that exercise, spirulina and exercise- spirulina caused a significant increase in ghrelin and obestatin compared to the pretest and control group. The ghrelin level of the exercise- spirulina group was significantly higher than the spirulina group. Also, the level of obestatin in the exercise- spirulina group was significantly higher than the exercise and spirulina groups.
Conclusion: It seems that aerobic exercise in combination with spirulina can help regulate hormones responsible for appetite in overweight elderly people.
Keywords
Aging
Obesity
Exercise
Spirulina
Appetite
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Journal of Isfahan Medical School
Volume 40, Issue 679
3rd Week, September
September and October 2022
Pages 509-516

  • Receive Date 07 September 2022