1
Professor, Department of Neurosurgery, Neuroscience Research Center, Al-Zahra Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2
assistant professor of neurosurgery, Fellowship of spine surgery, department of neurosurgery, Aja University of medical science, Tehran, Iran
3
department of neurosurgery, khatam al anbia hospitalTehran, Iran.
Abstract
Spondylodiscitis is a severe spinal infection that poses diagnostic and therapeutic challenges. The Surgical Infection Treatment and Severity (SITE) scoring system was developed to support surgical decision-making in infectious spinal diseases. This study aimed to assess the clinical applicability and supportive validity of the SITE scoring system in patients with de novo pyogenic spondylodiscitis. Methods: This retrospective analytical study included 165 adult patients with confirmed de novo spondylodiscitis who were managed either surgically or conservatively according to SITE-based criteria. Patients were divided into two severity groups (SITE < 8 and SITE ≥ 8). Clinical and radiological outcomes were assessed, and recovery was categorized as partial, full, or second full recovery. Sensitivity, specificity, and optimal cut-off values for predicting surgical need were determined using ROC curve analysis and Youden’s index. lskdflkesd Results: Among 165 patients (mean age 54.6 ± 14.7 years; 52% male), 61.2% underwent surgery. The SITE score showed acceptable association
Rezvani, M., Boustani, M. & Ahmadvand, A. ,. (2026). SITE scoring system for surgical decision-making in patients with spondylodiscitis: a retrospective clinical applicability study. (e33614). Journal of Isfahan Medical School, 44(878), e33614
MLA
Rezvani, M., Boustani, M., & Ahmadvand, A. ,. "SITE scoring system for surgical decision-making in patients with spondylodiscitis: a retrospective clinical applicability study" .e33614 , Journal of Isfahan Medical School, 44, 878, 2026, e33614.
HARVARD
Rezvani, M., Boustani, M., & Ahmadvand, A. ,. (2026). 'SITE scoring system for surgical decision-making in patients with spondylodiscitis: a retrospective clinical applicability study', Journal of Isfahan Medical School, 44(878), e33614.
CHICAGO
Rezvani, M., Boustani, M. & Ahmadvand, A. ,., "SITE scoring system for surgical decision-making in patients with spondylodiscitis: a retrospective clinical applicability study." Journal of Isfahan Medical School, 44 878 (2026): e33614,
VANCOUVER
Rezvani M., Boustani M., Ahmadvand A. ,. SITE scoring system for surgical decision-making in patients with spondylodiscitis: a retrospective clinical applicability study. JIMS. 2026;44(878):e33614 (In Persian).
