The Prevalence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor, Isfahan Kidney Disease Research Center AND Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate professor, Water and Electrolytes Research Center AND Department of Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran

5 Professor, Water and Electrolytes Research Center AND Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Acute kidney injury (AKI) is a complex syndrome defined as rapid decrease in glomerular filtration rate and therefore, retention of metabolic waste substances. The risk of AKI in candidates for coronary artery bypass graft (CABG) surgery usually is highlighted. The main objective of this study was to determine the AKI prevalence after CABG surgery.Methods: This observational study was performed on 1534 patients undergoing CABG surgery in Sina cardiac surgery center, Isfahan, Iran during 2006 till 2010. The information of patients was collected from hospital data sheet and recorded in a questionnaire. AKI was determined by laboratory data.Findings: 76.4% of the patients were men. The patients were 60.8 ± 8.9 years old with the average body mass index (BMI) of 27.0 ± 4.3 kg/m2. The prevalence of AKI was 49.1%. In overall, the hospital mortality rate was 2.7% and 0.7% of patients were assigned for dialysis.Conclusion: Our results indicated that the prevalence of AKI was considerably high. Special attention and hospital take cares are needed to reduce this prevalence.

Keywords

References

  1. Sharfuddin A, Weisboard SD, Palevsky PM, Molitoris BA. Acute kidney injury. In: Brenner BM, editor. Brenner & Rector's the Kidney. 9th ed. Philadelphia, PA: Saunders-Elsevier; 2012. p. 1045-69.
  2. Clarkson MR, Friedwald J, Eustace JA. Acute kidney injury. Brenner and Rector's The Kidney. Philadelphia, PA: Saunders; 2007. p. 943-87.
  3. Arora P, Kolli H, Nainani N, Nader N, Lohr J. Preventable risk factors for acute kidney injury in patients undergoing cardiac surgery. J Cardiothorac Vasc Anesth 2012; 26(4): 687-97.
  4. Mariscalco G, Lorusso R, Dominici C, Renzulli A, Sala A. Acute kidney injury: a relevant complication after cardiac surgery. Ann Thorac Surg 2011; 92(4): 1539-47.
  5. Li SY, Chen JY, Yang WC, Chuang CL. Acute kidney injury network classification predicts in-hospital and long-term mortality in patients undergoing elective coronary artery bypass grafting surgery. Eur J Cardiothorac Surg 2011; 39(3): 323-8.
  6. Vellinga S, Verbrugghe W, De Paep R, Verpooten GA, Janssen van Doorn K. Identification of modifiable risk factors for acute kidney injury after cardiac surgery. Neth J Med 2012; 70(10): 450-4.
  7. Parolari A, Pesce LL, Pacini D, Mazzanti V, Salis S, Sciacovelli C, et al. Risk factors for perioperative acute kidney injury after adult cardiac surgery: role of perioperative management. Ann Thorac Surg 2012; 93(2): 584-91.
  8. Greason KL, Sundt TM. Myocardial Revascularization with cardiopulmonary bypass. In: Cohn LH, editor. Cardiac Surgery in the Adult. 4th ed. New York, NY: McGraw-Hill Professional Publishing; 2012. p. 381-400.
Journal of Isfahan Medical School
Volume 31, Issue 251 - Serial Number 251
July and August 2013
Pages 1405-1412

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History

  • Receive Date: 25 August 2013
  • Revise Date:
  • Accept Date: 06 April 2022

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