The Efficiency and Safety of Temporary Cover Wound Dressing with Agicoat in Comparison with Allograft (Cadaver) in Burned Patients; A Randomized Clinical Trial Study

Document Type : Original Article (s)

Authors

1 Nurse, Imam Musa Kazem Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

2 Surgeon, Imam Musa Kazem Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

3 Infectious Disease Specialist, Imam Musa Kazem Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Early surgery to remove dead tissue with early closure of burn wounds has now been identified as one of the most important factors contributing to the survival of patients with major burn injuries. This study, the efficiency and safety of temporary cover wound dressing with agicoat was compared with allograft (cadaver) in burned patients.Methods: In this randomized clinical trial study, hospitalized patients in the age group of 18-45 years with burning of 20-30 percent and grade 2 deep and 3, were divided into two groups of control and test. Treatment was carried out in the operating room after debridement, covered with wounds or cadaver wounds, and patients were also treated for signs of infection such as warmth, discoloration, redness of the fluid, and fever. Patients were evaluated in two groups, and the surgeon checked the need for re-debridement, and recorded it in the checklist.Findings: A total of 50 burn patients met the inclusion criteria. Debridement in cadaver group was significantly lower than that of Agicoat group (P = 0.003). Mean pain score during the first to sixth days of surgery, and also on the ninth day of surgery was significantly lower in cadaver group (P < 0.050). The mean daily morphine injected over 24 hours was significantly lower in the cadaver group as well (P < 0.050).Conclusion: According to the findings of this study and other similar studies, it can be concluded that the use of cadaver reduces the need for debridement and morphine consumption in comparison with Agicoat.

Keywords

References

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Journal of Isfahan Medical School
Volume 38, Issue 599 - Serial Number 599
September and October 2021
Pages 837-841

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History

  • Receive Date: 29 September 2020
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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