Evaluating the Incidence of Postoperative Pancreatic Fistula after Pancreaticojujenostomy among the Cases of Whipple Surgery

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Pancreatic and Hepatobiliary and Transplant Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Department of Thoracic Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate Professor, Department of Pathology, School of Medicine AND Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Pancreaticouodenectomy (Whipple surgery) is the chosen treatment in patients with malignant or benign tumors of the pancreatic head. Pancreatic anastomosis is the most important part of Whipple surgery. Pancreatic fistula is the most common postoperative complication.Methods: This prospective study was conducted on patients with pancreatic tumor who went under pancreaticodoudenectomy and pancreaticojujenosotmy during the years 2011-2016 in Isfahancity, Iran. The incidence of postoperative pancreatic fistula was evaluated based on the criteria of International Study Group of Pancreatic Fistula (ISGPF). Data were analyzed using chi-square test via SPSS22 software. P-value < 0.05 considered significant.Findings: 82 patients participated in this survey. The rate of pancreatic fistula was 26 (31.7%) and 14 cases (17%) based on the right and left drainage, respectively. Although, there was meaningful relationship between the pancreatic fistula and pancreatic duct size, age, gender, pancreatic texture, and tumor histology had no effect on its incidence.Conclusion: Based on our analysis, a pancreatic duct less than 3 mm was considered a risk factor regarding the incidence of pancreatic fistula. In addition, the rate of pancreatic fistula was different based on the drainage location.

Keywords

References

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Journal of Isfahan Medical School
Volume 34, Issue 399 - Serial Number 399
July and August 2016
Pages 1106-1113

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History

  • Receive Date: 08 October 2016
  • Revise Date: 02 November 2024
  • Accept Date: 06 April 2022

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