Antibiotic Resistant Pattern in Escherichia Coli Derived from Outpatients and Inpatients with Urinary Tract Infections in Alzahra Hospital, Isfahan, Iran

Document Type : مقاله کوتاه

Authors

1 Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 MSc Student, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 PhD Student, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate Professor, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

-Background: Urinary tract infection (UTI) is one of the most frequent infectious diseases and can occur in all age groups. Due to various complications of urinary tract infections, timely and proper treatment seems important. This study aimed to assess the antibiotic resistant pattern in Escherichia coli derived from outpatients and inpatients with urinary tract infections in Alzahra Hospital, Isfahan, IranMethods: 135 isolates of Escherichia coli (from urine) were collected from September to February, 2013, from Alzahra Hospital (Isfahan, Iran). The samples were cultured on nutrient agar, Mac Conkey agar, Blood agar and Eosin methylene blue (EMB) agar. Bacterial susceptibility to antimicrobial agents was determined using Kirby-Bauer disk diffusion method as recommended by the Clinical and Laboratory Standards Institute (CLSI) guidelines.Findings: Among 135 Escherichia coli isolates, 91 isolates belonged to outpatients and 44 to inpatients. In total, 68% of the participants were women. Antibiotic resistance to ampicillin, ceftazidime, nalidixic acid and trimethoprim/sulfamethoxazole were higher than 50%. The rates of resistance to ceftazidime, ampicillin, trimethoprim/sulfamethoxazole, cefepime, and cefotaxime in outpatients were higher than in inpatients.Conclusion: Due to excessive use of antibiotics and increasing antibiotic resistance, it is necessary to perform antibiotic resistance tests routinely in laboratories.

Keywords

References

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Journal of Isfahan Medical School
Volume 34, Issue 415 - Serial Number 415
November and December 2017
Pages 1674-1679

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History

  • Receive Date: 23 October 2016
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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