Comparison of Quality of Life in Women Suffering from Cutaneous Leishmaniasis Treated with Topical and Systemic Glucantime along with Psychiatric Consultation Compared with the Group without Psychiatric Consultation

Document Type : Original Article(s)

Authors

1 Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

2 Assistant Professor, Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor , Skin Disease and Leishmaniasis Research Center, Department of Pharmacology and Toxicology, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan Iran

4 Student of Medicine, Skin Disease and Leishmaniasis Research Center And Student Research Committee, Isfahan University of Medical Sciences, Isfahan Iran

Abstract

Background: Cutaneous leishmaniasis (CL) is a parasitic disease which is endemic in Iran. Isfahan is one of the main centers of this disease. The aim of this study was to evaluate the effect of psychotherapy on quality of life (QOL) in women with CL treated with glucantime.Methods: In this study, 80 patients were randomly allocated to two groups, drug therapy and drug therapy plus psychotherapy. QOL was measured by dermatology life quality index (DLQI) and was compared at the beginning and the end of the intervention.Findings: The DLQI score before and after intervention in the group of drug therapy plus psychotherapy was 10.6 ± 5.7 and 7.7 ± 4.6, respectively, and their difference was statistically significant (P = 0.001). The score in drug therapy group before and after intervention was 10 ± 5.1 and 11 ± 5.1, respectively, which was not a significant difference. The mean difference of quality of life score before and after the treatment in the drug therapy plus psychotherapy group was 2.9 ± 5 and in the drug therapy group was 1.4 ± 4.2 (P < 0.001). Therefore, the quality of life was significantly higher in the patients treated with the combination of drug therapy and psychotherapy.Conclusion: Given the higher quality of life improvement by combination of psychotherapy and drug therapy in women with CL, psychiatric consultation is recommended.

Keywords

References

  1. Ardehali Rezaei N. Leishmania and leishmaniasis. Tehran, Iran: Iran University Press; 1985.
  2. Nilforoushzadeh MA, Sadeghian G. Cutaneous leishmaniasis. Isfahan, Iran: Orooj Publication; 2002.
  3. Asilian A. Cutaneous leishmaniasis and its treatment and prevention. Isfahan, Iran: Isfahan University of Medical Sciences Publications; 1992.
  4. The leishmaniases. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser 1984; 701: 1-140.
  5. Gupta MA, Gupta AK. Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. Br J Dermatol 1998; 139(5): 846-50.
  6. Hughes JE, Barraclough BM, Hamblin LG, White JE. Psychiatric symptoms in dermatology patients. Br J Psychiatry 1983; 143: 51-4.
  7. Koo J. The psychosocial impact of acne: patients' perceptions. J Am Acad Dermatol 1995; 32
  8. (5 Pt 3): S26-S30.
  9. Devrimci-Ozguven H, Kundakci TN, Kumbasar H, Boyvat A. The depression, anxiety, life satisfaction and affective expression levels in psoriasis patients. J Eur Acad Dermatol Venereol 2000; 14(4): 267-71.
  10. Picardi A, Abeni D, Melchi CF, Puddu P, Pasquini P. Psychiatric morbidity in dermatological outpatients: an issue to be recognized. Br J Dermatol 2000; 143(5): 983-91.
  11. van der Meeren HL, van der Schaar WW, van den Hurk CM. The psychological impact of severe acne. Cutis 1985; 36(1): 84-6.
  12. Cotterill JA, Cunliffe WJ. Suicide in dermatological patients. Br J Dermatol 1997; 137(2): 246-50.
  13. Kent G, Al'Abadie M. Psychologic effects of vitiligo: a critical incident analysis. J Am Acad Dermatol 1996; 35(6): 895-8.
  14. Finlay AY, Ryan TJ. Disability and handicap in dermatology. Int J Dermatol 1996; 35(5): 305-11.
  15. Yanik M, Gurel MS, Simsek Z, Kati M. The psychological impact of cutaneous leishmaniasis. Clin Exp Dermatol 2004; 29(5): 464-7.
  16. Jayaprakasam A, Darvay A, Osborne G, McGibbon D. Comparison of assessments of severity and quality of life in cutaneous disease. Clin Exp Dermatol 2002; 27(2): 306-8.
  17. Zachariae R, Zachariae C, Ibsen HH, Mortensen JT, Wulf HC. Psychological symptoms and quality of life of dermatology outpatients and hospitalized dermatology patients. Acta Derm Venereol 2004; 84(3): 205-12.
  18. Aronson NE, Sanders JW, Moran KA. In harm's way: infections in deployed American military forces. Clin Infect Dis 2006; 43(8): 1045-51.
Journal of Isfahan Medical School
Volume 29, Issue 173 - Serial Number 173
November and December 2012
Pages 3046-3052

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History

  • Receive Date: 12 March 2012
  • Revise Date:
  • Accept Date: 06 April 2022

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