Document Type : Original Article (s)
Authors
1
Professor, Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2
Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Glioma is a type of brain tumor that occurs in the brain and spinal cord and is derived from glial cells. Frequency, survival and response to therapy in these tumors are dependent on age and sex. The survival rate varies from several months to years. In the current study, 3-year survival rate in patients with all kinds of glioma tumors who were hospitalized in Alzahra hospital, Isfahan, Iran, in the years 2001-2010 were evaluated.Methods: In the current study, the target population was the patients with all kinds of proven glioma who had resection surgery. The volume of the population was determined as all the patients with all kinds of glioma tumors in the years 2001-2010, who were operated in Alzahra hospital. The total number of patients was 490. Inclusion criteria were patient’s tendency for participation in the study, the accuracy of the patient’s basic information in the archive documents and lack of death at the hospital, in pre-, intra- and postoperation periods. According to these criteria, only 221 were eligible for inclusion. The information such as name, family, age, gender, tumor type, treatment type and telephone number were extracted from the list of the patients. The patients were contacted and questionnaires were completed. Microsoft Excel software was used for data analysis, so that its data were the number of people with any type of tumor, age, sex of the patients and the three-year survival rate of any tumor.Findings: The three-year survival was 8.7% in glioblastoma multiform, 100% in diffuse astrocytoma, epondymoma and pilocytic astrocytoma, 95.2% in oligodandroglioma, and zero in anaplastic astrocytoma.Conclusion: In this study, surgery plus radiotherapy in diffuse astrocytoma, oligodandroglioma and epondymoma increased three-year survival rate. In pilocytic astrocytoma surgery, as the first treatment, increased the three-year survival. In the case of glioblastoma multiform and anaplastic astrocytoma, surgery plus radiotherapy with or without chemotherapy briefly play role in increasing the survival rate.
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