Comparing the Patterns of Hypertension and Type 2 Diabetes Mellitus in Patients with Colorectal Cancer

Document Type : Original Article (s)

Authors

1 Assistant Professor, Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran

2 Assistant Professor, Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 Research and Technology Deputy, Shahrekord University of Medical Sciences, Shahrekord, Iran

4 Professor, Department of Nephrology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Type 2 diabetes mellitus (DM) and hypertension are worldwide epidemic. Colorectal cancer (CRC) is the most prevalent gastrointestinal cancer in Iran. Prevalence of type 2 diabetes mellitus and hypertension in the patients with colorectal cancer had not reported in Iran, before this study.Methods: Overall, 2570 individual-year follow-ups were conducted for 1127 patients with colorectal cancer. For diagnosis of type 2 diabetes mellitus, fasting blood sugar and glycosylated hemoglobin tests were used and for that of hypertension, blood pressure was measured in two turns. The descriptive indices were calculated and the mean and median survivals, from colorectal cancer diagnosis time, were calculated using survival analysis and the comparison among survival times was done through log-rank test. Stata12 software  was used for data analysis.Findings: The prevalences of hypertension and type 2 diabetes mellitus in the patients with colorectal cancer were 13.38% (95% CI: 11.1-15.8) and 8.69% (95% CI: 7.0-10.7), respectively. Median survival time in patients with hypertension and diabetes mellitus were 8.52 and 4.90 years, respectively. According to log-rank test, no significant difference was observed between the survival time of patients with colorectal cancer suffering from hypertension and type 2 diabetes mellitus.Conclusion: The obtained findings in this study indicate that survival time in patients with type 2 diabetes mellitus is less than those with hypertension; but two metabolic diseases have same effect on survival rate of the patients with colorectal cancer.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 302 - Serial Number 302
July and August 2014
Pages 1537-1545

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History

  • Receive Date: 20 June 2014
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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