Effects of Nanosilver Dressing on Wounds Created in Rats

Document Type : Original Article (s)

Authors

1 Scientific Society of Nanotechnology, Yazd Branch, Islamic Azad University, Yazd, Iran

2 General Practitioner, Scientific Society of Medicine, Yazd Branch, Islamic Azad University, Yazd, Iran

3 Assistant Prorfessor, Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract

Background: Nowadays dressing sterilization and management of wound infection costs a lot. Nanosilver is a nanotechnology product with antimicrobial property. It can improve efficiency, reduce cost and increase antibacterializing durability and performance of textiles. This study was performed to determine the efficacy of nanosilver dressing in wound recovery in rats.Methods: In this experimental study, 10 rats were divided into 2 groups of 5. After anesthesia, superficial wounded of equal size were made on the shaved backs of all animals. The first group was dressed by nanosilver dressing while the second group was dressed by none nanosilver dressing. Then, wound areas were measured every 2 days for 12 days. Data was analyzed using analysis of variance (ANOVA).Findings: The recovery period among the rats bandaged with nanosilver dressing was significantly shorter than the other group (P < 0.05). In addition, less side effects were observed in the group treated with nanosilver dressing.Conclusion: According to our findings, nanosilver dressing can be effective in controlling superficial wound infection. Nanosilver dressing can also improve deep infections caused by thermal, chemical and electrical burns.

Keywords

References

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Journal of Isfahan Medical School
Volume 29, Issue 164 - Serial Number 164
September and October 2012
Pages 2073-2078

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History

  • Receive Date: 14 March 2011
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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