Recording of Electrophysiological Changes and Sensory Function by Conduit Containing Stem Cells, Gold Nanoparticles and Neurotrophic Factor after Sciatic Nerve Regeneration

Document Type : Original Article (s)

Authors

1 PhD, Department of Medicine, Clinical Research Development Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran

2 PhD, Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran

3 Professor, Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Organophosphorus poisoning is one of the most common and dangerous causes of pesticide poisoning. We compared the clinical manifestations and outcomes between organophosphate poisoning patients with and without aspiration pneumonia. We also determined the predictive risk factors for aspiration pneumonia.
Methods: This cross-sectional study was conducted at the Poisoning Referral Center in Khorshid Hospital, affiliated with Isfahan University of Medical Sciences, Isfahan, Iran. Patients with organophosphate poisoning aged over 18 years were included in the study from April 2018 to September 2022. A binary logistic regression test was used to find the predictive factors for aspiration pneumonia.
Findings: 217 patients were evaluated in the study. Most of them were men (62.2%) with an average age (SD) of 38.2 (16.5). Aspiration pneumonia was observed in 11.52% of patients. The mortality rate in the two groups with and without aspiration pneumonia was 28% and 3.6%, respectively (P < 0.001). Patients with aspiration pneumonia were older and had higher frequency of addiction and underlying somatic disease (P < 0.05). The frequency of coma, muscarinic symptoms, tremors, decreased blood oxygen saturation, and endotracheal intubation on admission were higher in patients with aspiration pneumonia (P < 0.05).
Conclusion: Although the above factors were different between the group with and without aspiration pneumonia, regression analysis showed that only the history of addiction, underlying somatic disease, sweating, miotic pupils, abnormal lung auscultation, and endotracheal intubation before or at admission were predictive factors.

Highlights

Shahnaz Razavi : PubMed, Google Scholar 

Keywords

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References

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Journal of Isfahan Medical School
Volume 41, Issue 727
3rd Week, September
September and October 2023
Pages 566-574

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History

  • Receive Date: 15 November 2021
  • Accept Date: 26 August 2023

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