Document Type : Original Article (s)
Authors
1
PhD Student, Department of Exercise Physiology, School of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran And Faculty Member, Department of Physical Education and Sport Sciences, Jahrom University, Jahrom, Iran
2
Professor, Department of Exercise Physiology, School of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran, Iran
3
Associate Professor, Department of Exercise Physiology, School of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran, Iran
4
Assistant Professor, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Background: In order to evaluate the relation between exercise and cytokines, we examined the effects of an 8-week endurance training course and recovery period on changes in interferon gamma (IFN-ϒ) and leukocyte subsets with recovery period. Methods: In this study, 30 healthy young male volunteers who aged 18-25 years were randomized into endurance training group and control group. The first group completed the endurance training protocol (running on a treadmill for 15-30 min at 50%-70% maximal heart rate) for 8 weeks. Venous blood samples were taken in both groups before, immediately after, and 24 and 48 hours after exercise. Findings: We found that IFN-ϒ levels in the trained group decreased after the 4th and 8th weeks (mid- and post-exercise, respectively), and also after 24-hour and 48-hour recovery periods. Leukocyte subsets on the other hand, decreased from pre-exercise until 24 hours after exercise. Conclusion: Our results demonstrated that a period of endurance exercise led to changes in IFN-ϒ levels after exercise and recovery periods. Keywords: Endurance training, Cytokine, Interferon gamma, Recovery period
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