Relationship of Personality Traits, Chronic Fatigue and Serum IgM Level in Patients with Sleep Deprivation

Document Type : Original Article (s)

Authors

1 Assistant Professor, Department Psychology, Islamic Azad University, Naein Branch, Naein, Iran

2 Assistant Professor, Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Professor, Department of Psychology, School of Psychology and Education Science, University of Isfahan, Isfahan, Iran

4 Associate Professor, Behavioral Sciences Research Center AND Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Employees in night shift experience sleep deprivation continuously. Stress-induced insomnia affects on fatigue and reduces maximum activity. During the shifts, hormonal changes affect on immunoglobulin M (IgM) operation. Individual differences in encounterring and adaptation with shift-induced stress can be effective to determine vulnerability. The aim of this research was to assess the relationship of personality traits, chronic fatigue and serum IgM level in patients with sleep deprivation.Methods: The study population was the shift employees in steel factories in Isfahan, Iran. A total number of 221 male employees were selected with random cluster sampling. Personality traits, (Eysnek and Freidman), and chronic fatigue (Barton et al.) questionnaires were used to assess research variables. IgM was determined with nephelometric method. Data were analyzed using Pearson's correlation coefficient and structure equation modeling.Findings: Neurosis, introversion and A type personality correlated significantly with chronic fatigue (P < 0.01). Type A personality and neurosis correlated with serum IgM level, too (P < 0.01). Indirect effect of neurosis, introversion and A type personality on serum IgM level was significant (P < 0.01).Conclusion: This research argued employees with neurosis, A type personality, and introversion traits are talented for reducing serum IgM level.

Keywords

References

  1. Rawlins RP, Williams SR, Beck CK. Mental health-psychiatric nursing. Philadelphia, PA: Mosby; 1993.
  2. Lima PF, Medeiros AL, Araujo JF. Sleep-wake pattern of medical students: early versus late class starting time. Braz J Med Biol Res 2002; 35(11): 1373-7.
  3. Ayas NT, White DP, Manson JE, Stampfer MJ, Speizer FE, Malhotra A, et al. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med 2003; 163(2): 205-9.
  4. Leproult R, Copinschi G, Buxton O, Van CE. Sleep loss results in an elevation of cortisol levels the next evening. Sleep 1997; 20(10): 865-70.
  5. Swaab DF, Slob AK, Houtsmuller EJ, Brand T, Zhou JN. Increased number of vasopressin neurons in the suprachiasmatic nucleus (SCN) of 'bisexual' adult male rats following perinatal treatment with the aromatase blocker ATD. Brain Res Dev Brain Res 1995; 85(2): 273-9.
  6. Folkard S. Do permanent night workers show circadian adjustment? A review based on the endogenous melatonin rhythm. Chronobiol Int 2008; 25(2): 215-24.
  7. Jerjes WK, Cleare AJ, Wessely S, Wood PJ, Taylor NF. Diurnal patterns of salivary cortisol and cortisone output in chronic fatigue syndrome. J Affect Disord 2005; 87(2-3): 299-304.
  8. Nagai M, Morikawa Y, Kitaoka K, Nakamura K, Sakurai M, Nishijo M, et al. Effects of fatigue on immune function in nurses performing shift work. J Occup Health 2011; 53(5): 312-9.
  9. Carrillo-Vico A, Guerrero JM, Lardone PJ, Reiter RJ. A review of the multiple actions of melatonin on the immune system. Endocrine 2005; 27(2): 189-200.
  10. Nelson RJ, Drazen DL. Melatonin mediates seasonal changes in immune function. Ann N Y Acad Sci 2000; 917: 404-15.
  11. Irwin M, Mascovich A, Gillin JC, Willoughby R, Pike J, Smith TL. Partial sleep deprivation reduces natural killer cell activity in humans. Psychosom Med 1994; 56(6): 493-8.
  12. Brooks KP, Robles TF. Recent depressive and anxious symptoms predict cortisol responses to stress in men. Psychoneuroendocrinology 2009; 34(7): 1041-9.
  13. Spreng M. Cortical Excitations, Cortisol Excretion and Estimation of Tolerable Nightly Over-Flights. Noise Health 2002; 4(16): 39-46.
  14. Barrett KE, Barman SM, Boitano S, Brooks H. Ganong's review of medical physiology. 24th ed. New York, NY: McGraw-Hill; 2012.
  15. Guyton A, Hall J. Textbook of medical physiology. 11th ed. Philadelphia, PA: Saunders; 2005.
  16. Segerstrom SC, Miller GE. Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychol Bull 2004; 130(4): 601-30.
  17. Abbas AK, Lichtman A, Pober JS. Cellular and molecular immunology. 3rd ed. Philadelphia, PA: Saunders; 1997.
  18. Casale G, Marinoni GL, d'Angelo R, de,Nicola P. Circadian rhythm of immunoglobulins in aged persons. Age Ageing 1983; 12(1): 81-5.
  19. Pevet P. Melatonin and biological rhythms. Biol Signals Recept 2000; 9(3-4): 203-12.
  20. Tucker P, Knowles SR. Review of studies that have used the Standard Shiftwork Index: evidence for the underlying model of shiftwork and health. Appl Ergon 2008; 39(5): 550-64.
  21. Gerdin MJ, Masana MI, Dubocovich ML. Melatonin-mediated regulation of human MT(1) melatonin receptors expressed in mammalian cells. Biochem Pharmacol 2004; 67(11): 2023-30.
  22. Harma M. Circadian adaptation to shift work. In: Folkard S, Costa G, Knauth P, Hornberger S, editors. Shiftwork in the 21st Century. New York, NY: Peter Lang GmbH; 2000. p. 125-30.
  23. Davison G, Neale J. Abnormal psychology. 8th ed. New York, NY: John Wiley and sons; 2000.
  24. Takahashi M, Tanigawa T, Tachibana N, Mutou K, Kage Y, Smith L, et al. Modifying effects of perceived adaptation to shift work on health, wellbeing, and alertness on the job among nuclear power plant operators. Ind Health 2005; 43(1): 171-8.
  25. Kobasa SC, Maddi SR, Kahn S. Hardiness and health: a prospective study. J Pers Soc Psychol 1982; 42(1): 168-77.
  26. Cohen S, Williamson GM. Stress and infectious disease in humans. Psychol Bull 1991; 109(1): 5-24.
  27. Rabin BS, Cohen S, Ganguli R, Lysle DT, Cunnick JE. Bidirectional interaction between the central nervous system and the immune system. Crit Rev Immunol 1989; 9(4): 279-312.
  28. Nurzynska A. The number and types of health behaviors depending on chronotype and temperamental traits [MSc Thesis]. Warsaw, Poland: University of Warsaw, School of Psychology; 2007.
  29. Rosenman RH, Chesney MA. The relationship of type A behavior pattern to coronary heart disease. Act Nerv Super (Praha) 1980; 22(1): 1-45.
  30. Ireland JL, Boustead R, Ireland CA. Coping style and psychological health among adolescent prisoners: a study of young and juvenile offenders. J Adolesc 2005; 28(3): 411-23.
  31. Pitsopoulos CN, Greenwood KM. Shift-dependent differences in self-reporting of health symptoms among shiftworkers. Int J Ind Ergon 2004; 34(3): 187-93.
  32. Knowles SR, Bull DF. Assessing the relationship between age and personality variables measured by the standard shiftwork index on the psychological and physiological well-being of police officers. Canadian Journal of Police and Social Services 2004; 2(1): 437-44.
  33. Khaleghipour Sh, Bagherian- Sararoudi R. Relationship between circadian type, chronic fatigue and M immunoglobulin serum level in shift staff. J Res Behav Sci 2013; 10(7): 645-53.
  34. Barton J, Spelten E, Totterdell P, Smith L, Folkard S, Costa G. The standard shiftwork index: a battery of questionnaires for assessing shiftwork-related problems. Work and Stress 1995; 9 (1): 4–30.
  35. Shakhar K, Valdimarsdottir HB, Guevarra JS, Bovbjerg DH. Sleep, fatigue, and NK cell activity in healthy volunteers: significant relationships revealed by within subject analyses. Brain Behav Immun 2007; 21(2): 180-4.
  36. Haus E, Smolensky M. Biological clocks and shift work: circadian dysregulation and potential long-term effects. Cancer Causes Control 2006; 17(4): 489-500.
  37. Okamoto H, Tsunoda T, Teruya K, Takeda N, Uemura T, Matsui T, et al. An occupational health study of emergency physicians in Japan: health assessment by immune variables (CD4, CD8, CD56, and NK cell activity) at the beginning of work. J Occup Health 2008; 50(2): 136-46.
  38. Pier GB, Lyczak JB, Wetzler LM. Immunology, Infection, and Immunity. Washington, DC: American Society for Microbiology Press, 2004.
  39. Harma M. Sleepiness and shiftwork: individual differences. J Sleep Res 1995; 4(S2): 57-61.
  40. Diaz-Morales JF. Morning and evening-types: exploring their personality styles. Pers Individ Dif 2007; 43(4): 769–78.
  41. Croiset G, Heijnen CJ, van der Wal WE, de Boer SF, de Wied D. A role for the autonomic nervous system in modulating the immune response during mild emotional stimuli. Life Sci 1990; 46(6): 419-25.
Journal of Isfahan Medical School
Volume 31, Issue 242 - Serial Number 242
May and June 2013
Pages 923-932

Files

History

  • Receive Date: 28 August 2012
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics