Effect of Aerobic Training on Concentration of Plasma Angiotensin-Converting Enzyme (ACE) in Postmenopausal Women

Document Type : Original Article (s)

Authors

1 Department of Exercise Physiology, School of Physical Education and Sport Science, University of Mazandaran, Babolsar, Iran

2 Associate Professor, Department of Exercise Physiology, School of Physical Education and Sport Science, University of Mazandaran, Babolsar, Iran

3 Assistant Professor, Department of Exercise Physiology, School of Physical Education and Sport Science, University of Mazandaran, Babolsar, Iran

Abstract

Background: Angiotensin converting enzyme (ACE) is secreted from vascular endothelium. This enzyme is one of the main determinants of blood pressure regulation. This study aimed to investigate the effect of aerobic training on plasma concentration of angiotensin-converting enzyme in postmenopausal women.Methods: 14 postmenopausal women (40-65 years old) were enrolled. Plasma levels of angiotensin-converting enzyme, anthropometric indices, maximal oxygen uptake (VO2max), and systolic and diastolic blood pressure were measured before and after a training program. The exercise intensity started by 40-45% of maximum heart rate reserve for the first week and gradually received to 70-80% of maximum heart rate reserve in eight weeks.Findings: The plasma levels of angiotensin-converting enzyme after 8 weeks of aerobic exercise significantly increased (P = 0.020). In addition, a significant decrease in waist circumference was observed (P < 0.001). Maximal oxygen uptake increased significantly, too (P < 0.001). There was significant negative correlation between the changes in angiotensin-converting enzyme and the changes in waist circumference (P = 0.020, r = -0.601), weight (P = 0.020, r = -0.63) and body mass index (BMI) (P = 0.010, r = -0.637).Conclusion: This study indicated that aerobic training could increase plasma levels of angiotensin-converting enzyme in postmenopausal women, without significant changes in body composition and blood pressure. Further studies with more numbers of subjects are needed to confirm these results.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 310 - Serial Number 310
September and October 2015
Pages 1965-1975

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History

  • Receive Date: 08 October 2013
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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