The Correlation between the Histopathological Findings of Endometrial Curettage and Hysterectomy

Document Type : Original Article(s)

Authors

1 Assistant Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Medical Student, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Dilatation and curettage (D&C) has been the method of choice for obtaining endometrial sample but there is a challenge about the D&C’s accuracy and reliability compared to other diagnostic methods. The aim of this study was to investigate the concordance between endometrial histopathological diagnosis from D&C and hysterectomy samples.
Methods: In this retrospective study, histopathological results of D&C samples of 136 women who suffered from abnormal uterine bleeding between 2015 to 2018 and underwent hysterectomy were investigated and compared with pathologic reports of hysterectomy.
Findings: The mean ± standard deviation (SD) of age of patients was 52.6 ± 11.3 years in the range of 33-80 years. According to the findings of D&C in comparison with the standard method of hysterectomy, the specificity and negative predictive values were substantial in premalignant samples. Beside, D&C findings revealed the specificity and the positive predictive values as likely as 100% for diagnosing malignant samples. In the other hand, D&C revealed significant the sensitivity and the positive predictive values for diagnosing normal and benign samples. In the premalignant pathologies that were diagnosed with D&C, the risk of an undetected malignancy in the atypical hyperplasia was 16.7%.
Conclusion: No malignant pathology was encountered in patient with a diagnosis of normal tissue or a benign pathology on the D&C samples. In addition, both the specificity and the positive predictive values following D&C was 100% in diagnosing endometrial malignancy.

Keywords

References

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Journal of Isfahan Medical School
Volume 40, Issue 701
1st Week,, March
March and April 2023
Pages 1067-1073

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