Pityriasis Rubra Pilaris Following Exposure to Dolomite

Document Type : Case Report

Authors

1 Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran AND Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background: Pityriasis rubra pilaris (PRP) is a rare skin disease characterized by follicular hyperkeratosis and prefollicular erythema with islands of normal skin scattered among erythematous patches with desquamation.Case Report: In this case report, we present a 30-year-old man who developed pityriasis rubra pilaris (PRP) following exposure to dolomite.Conclusion: The diagnosis of PRP was confirmed histologically and the patient was successfully treated with acitretin and cyclosporine. 

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  1. Griffiths WAD, Judge MR, Leigh IM. Disorder of keratinization. In: Champion RH, Burton JL, Burns DA, Breathnach SM, editors. Textbook of dermatology. Oxford, UK: Black well Science; 1998. p. 1539-45.
  2. Betto P, Vassilopoulou A, Colombari R, Veller-Fornasa C. Acute juvenile pityriasis rubra pilaris: a case report after mononucleosis infection. G Ital Dermatol Venereol 2008; 143(4): 271-3.
  3. Klein A, Landthaler M, Karrer S. Pityriasis rubra pilaris: a review of diagnosis and treatment. Am J Clin Dermatol 2010; 11(3): 157-70.
  4. Moreschi E, Hernandes L, Dantas JA, da Silva MA, Casaroto AR, Bersani-Amado CA. Effect of dolomite on the repair of bone defects in rats: histological study. Histol Histopathol 2010; 25(12): 1547-56.
  5. Belsito DV. The immunologic basis of patch testing. J Am Acad Dermatol 1989; 21(4 Pt 2): 822-9.