Effect of Crocin on Inflammatory Bowel Diseases

Document Type : Review Article

Authors

1 MSc Student, Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Assistant Professor, Metabolic syndrome Research center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Assistant Professor, Department of Clinical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Professor, Department of Physiology AND Neurogenic Inflammation Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Inflammatory bowel diseases (IBDs) are among important gastrointestinal diseases in human and include ulcerative colitis and Crohn's disease. Although the prevalence of these diseases in developed countries is high, however, their prevalence is increasing in developing countries such as Iran, too. Treatment of inflammatory bowel diseases at the early stages is very important because of chronic inflammation and its complications on different parts of the body. One of the most important consequences of chronic inflammation is colitis-induced colon cancer. Saffron is a traditionally herbal drug used by people in Asia especially Iran. It has several beneficial effects on the body especially as anti-oxidant, anti-inflammatory and anti-cancer. In this paper, we reviewed the effect of crocin on inflammation process especially in inflammatory bowel diseases.

Keywords

References

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Journal of Isfahan Medical School
Volume 34, Issue 414 - Serial Number 414
November and December 2017
Pages 1640-1647

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History

  • Receive Date: 11 December 2016
  • Revise Date:
  • Accept Date: 06 April 2022

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