Comparison of Radioisotope Scan and Ultrasonography in Diagnosis of Gastroesophageal Reflux in 2-13-Year-Old Children

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: The aim of this study was to compare radionuclide scintigraphy and ultrasonography in the diagnosis of gastroesophageal reflux in 2-13-year-old children who referred to a pediatric clinic in Isfahan city, Iran, during 2014-2015.Methods: In across-sectional study, 150 children aged 2 to13 years with symptoms of gastroesophageal reflux were assessed using ultrasound and radioisotope scan. All of them were treated using the drug omeprazole for 6 weeks; and finally, the diagnostic values were compared between the two methods.Findings: Sensitivity, specificity, and negative and positive predictive values were 96.1%, 68.2%, 94.6%, and 75.0%, and 85.2%, 45.5%, 90.1%, and 34.5%, in radioisotope scan and ultrasonography, respectively.Conclusion: Radioisotope scan and ultrasonography do not have enough accuracy in diagnosis of gastroesophageal reflux in children. Using empirical therapy in diagnosis is depended on the duration of disease, too. Using combination of ultrasound and radioisotope scans is recommended in long-duration disease or when the case is suspicious to other diseases such as tumors and malignancy.

Keywords

References

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Journal of Isfahan Medical School
Volume 35, Issue 427 - Serial Number 427
March and April 2017
Pages 447-452

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History

  • Receive Date: 14 May 2016
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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