The Efficacy of Oral Hydrogel Containing Hyaluronic Acid, Polyvinylpyrrolidone, and Glycyrrhizin for Prevention and Treatment of Oral Mucositis Induced by Chemotherapy

Document Type : Original Article (s)

10.22122/jims.v38i607.13550

Sonis S. Mucositis: The impact, biology and therapeutic opportunities of oral mucositis. Oral oncology 2009; 45: 1015-20.
Al-Ansari S, Zecha JA, Barasch A, de Lange J, Rozema FR, Raber-Durlacher JE. Oral mucositis induced by anticancer therapies. Curr Oral Health Rep 2015; 2(4): 202-11.
Maria OM, Eliopoulos N, Muanza T. Radiation-induced oral mucositis. Front Oncol 2017; 7: 89.
Oronsky B, Goyal S, Kim MM, Cabrales P, Lybeck M, Caroen S, et al. A review of clinical radioprotection and chemoprotection for oral mucositis. Transl Oncol 2018; 11(3): 771-8.
Campos MI, Campos CN, Aarestrup FM, Aarestrup BJ. Oral mucositis in cancer treatment: Natural history, prevention and treatment. Mol Clin Oncol 2014; 2(3): 337-40.
Georgiou M, Patapatiou G, Domoxoudis S, Pistevou-Gompaki K, Papanikolaou A. Oral Mucositis: Understanding the pathology and management. Hippokratia 2012; 16(3): 215-6.
Alvarino-Martin C, Sarrion-Perez MG. Prevention and treatment of oral mucositis in patients receiving chemotherapy. J Clin Exp Dent 2014; 6(1): e74-e80.
Tanideh N, Rokhsari P, Mehrabani D, Mohammadi SS, Sabet SF, Ashraf MJ, et al. The healing effect of licorice on Pseudomonas aeruginosa infected burn wounds in experimental rat model. World J Plast Surg 2014; 3(2): 99-106.
Takhshid MA, Mehrabani D, Ai J, Zarepoor M. The healing effect of licorice extract in acetic acid-induced ulcerative colitis in rat model. Comp Clin Path 2012; 21(6): 1139-44.
Brogden RN, Speight TM, Avery GS. Deglycyrrhizinised liquorice: A report of its pharmacological properties and therapeutic efficacy in peptic ulcer. Drugs 1974; 8(5): 330-9.
Buchsel PC. Polyvinylpyrrolidone-sodium hyaluronate gel (Gelclair): A bioadherent oral gel for the treatment of oral mucositis and other painful oral lesions. Expert Opin Drug Metab Toxicol 2008; 4(11): 1449-54.
Rezazadeh M, Jafari N, Akbari V, Amirian M, Tabbakhian M, Minaiyan M, et al. A mucoadhesive thermosensitive hydrogel containing erythropoietin as a potential treatment in oral mucositis: In vitro and in vivo studies. Drug Deliv Transl Res 2018; 8(5): 1226-37.
Barasch A, Epstein J, Tilashalski K. Palifermin for management of treatment-induced oral mucositis in cancer patients. Biologics 2009; 3: 111-6.
Kogan G, Soltes L, Stern R, Gemeiner P. Hyaluronic acid: A natural biopolymer with a broad range of biomedical and industrial applications. Biotechnol Lett 2007; 29(1): 17-25.
Anilkumar TV, Muhamed J, Jose A, Jyothi A, Mohanan PV, Krishnan LK. Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound. Biologicals 2011; 39(2): 81-8.
Price RD, Myers S, Leigh IM, Navsaria HA. The role of hyaluronic acid in wound healing: assessment of clinical evidence. Am J Clin Dermatol 2005; 6(6): 393-402.