Background: The scaphoid fractures are of the most prevalent fractures of the wrist and there are different ways for the treatment of these fractures. The aim of this study was to compare results and complications of three of these methods.Methods: In this randomized clinical-trial study, among patients referred to Kashani hospital in Isfahan, Iran, from September 2006 to September 2008, 39 with scaphoid fracture, with more than 1 mm displacement, were enrolled. They were randomly assigned into three groups (13 patients in each). In the first group, close reduction and immobilization (cast) was used. In the second group, percutaneous fixation with pin and in the thirdgroup, one percutaneous screw was used. The patients were evaluated monthly with X-Ray, and by Mayo Wrist Scoring. The evaluated information was obtained and compared.Findings: The mean time of union was significantly shorter in the third group and there was no malunion, nonunion or any other complication in this group. Results of Mayo Wrist Scoring were better in third group, too.Conclusion: The percutaneous screw fixation in scaphoid fractures causes better fixation and results in shortening of union period and, if technically possible, can be suggested as a good method of treatment for these types of fractures.