Six-Minute Walking Test in Comparison with Spirometry Variables in Can-didates for Thoracotomy

Document Type : Original Article (s)

Authors

1 Resident Professor, Department of Intermal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Assistant Professor, Department of Intermal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Resident, Department of Intermal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: The six-minute walk test (6MWT) is a good index of physical function and therapeutic response in patients with chronic lung disease. The aim of present study was comparison six-minute walking test with spirometry variables in patients who were candidates for thoracotomy.Methods: In this descriptive-analytic study, 65 patients, who were candidates for thoracotomy, recruited from Al-Zahra Hospital in Isfahan, Iran by simple nonrandom sampling. At the beginning of the study, spirometry then the six-minute walk test was performed in the patients. Also, measurements of oxygen saturation and pulse rate during exercise and distance walked during six minutes were obtained. Three patients were unable to performed six-minute walk test and excluded. Data were collected and analyzed for 65 patients.Finding: The mean age of patients was 44.8 ± 14.2 years. Mean distance walked during six minutes was 427.27 ± 98 meters. There was significant association between mean of distance walked during six minutes and FEV1 dosage (r = 0.5; P = 0.043). There was no significant association between mean of distance walked during six minutes and age (r = -0.15; P = 0.5).Conclusion: The results of this study demonstrated that there is significant association between mean of 6MWT with FEV1 but more studies are needed to assay the relations among 6MWT and spirometry variables.

Keywords


  1. Hoeper MM, Markevych I, Spiekerkoetter E, Welte T, Niedermeyer J. Goal-oriented treatment and combination therapy for pulmonary arterial hypertension. Eur Respir J 2005; 26(5): 858-63.
  2. Hoeper MM, Oudiz RJ, Peacock A, Tapson VF, Haworth SG, Frost AE, et al. End points and clinical trial designs in pulmonary arterial hypertension: clinical and regulatory perspectives. J Am Coll Cardiol 2004; 43(12 Suppl S): 48S-55S.
  3. American Thoracic Society. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med 2002; 166(1): 111-7.
  4. Cooper DM, Weiler-Ravell D, Whipp BJ, Was-serman K. Aerobic parameters of exercise as a function of body size during growth in children. J Appl Physiol 1984; 56(3): 628-34.
  5. Ong KC, Chong WF, Soh C, Earnest A. Com-parison of different exercise tests in assessing outcomes of pulmonary rehabilitation. Respir Care 2004; 49(12): 1498-503.
  6. Solway S, Brooks D, Lacasse Y, Thomas S. A qualitative systematic overview of the measurement properties of functional walk tests used in the cardiorespiratory domain. Chest 2001; 119(1): 256-70.
  7. Kessler R, Faller M, Fourgaut G, Mennecier B, Weitzenblum E. Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 159(1): 158-64.
  8. Gulmans VA, van Veldhoven NH, de Meer K, Helders PJ. The six-minute walking test in children with cystic fibrosis: reliability and validity. Pediatr Pulmonol 1996; 22(2): 85-9.
  9. Bittner V, Weiner DH, Yusuf S, Rogers WJ, McIntyre KM, Bangdiwala SI, et al. Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. SOLVD Investigators. JAMA 1993; 270(14): 1702-7.
  10. Miyamoto S, Nagaya N, Satoh T, Kyotani S, Sakamaki F, Fujita M, et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. Am J Respir Crit Care Med 2000; 161(2 Pt 1): 487-92.
  11. Austin KG, Mengelkoch L, Hansen J, Shahady E, Sirithienthad P, Panton L. Comparison of oxygenation in peripheral muscle during submaximal aerobic exercise, in persons with COPD and healthy, matched-control persons. Int J Chron Obstruct Pulmon Dis 2006; 1(4): 467-5.