Thyroid or Parathyroid Adenoma?

Document Type : Case Report

Authors

1 Assistant Professor, Department of Rheumatology, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Assistant Professor, Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Associate Professor, Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: The diagnosis of hyperparathyroidism is usually first suspected because of the finding of an elevated serum calcium concentration. The clinical presentation may be subtle and hypercalcemia may be mild. Single adenomas account for most cases of primary hyperparathyroidism. One of the atypical presentations includes normocalcemic primary hyperparathyroidism. Thyroid nodules come to clinical attention when noted by the patient, or as an incidental finding during the routine physical examination, or during a para clinical procedure. Ultrasound is also recommended for all patients to confirm the presence of nodularity. Fine-needle aspiration (FNA) biopsy is the most accurate method for evaluating thyroid nodules. Thyroid scintigraphy is used to determine the functional status of a nodule.Case report: In this study, we report a case of huge parathyroid adenoma and thyroid adenoma in the same time in a patient with nonspecific generalized body pain. Primary clinical and para clinical findings did not have any correlation with each other and could not guide us to the correct diagnosis.

Keywords

References

  1. Hegedus L. Clinical practice. The thyroid nodule. N Engl J Med 2004; 351(17): 1764-71.
  2. Steele SR, Martin MJ, Mullenix PS, Azarow KS, Andersen CA. The significance of incidental thy-roid abnormalities identified during carotid du-plex ultrasonography. Arch Surg 2005; 140(10): 981-5.
  3. Marqusee E, Benson CB, Frates MC, Doubilet PM, Larsen PR, Cibas ES, et al. Usefulness of ul-trasonography in the management of nodular thyroid disease. Ann Intern Med 2000; 133(9): 696-700.
  4. Castro MR, Gharib H. Continuing controversies in the management of thyroid nodules. Ann In-tern Med 2005; 142(11): 926-31.
  5. Dige-Petersen H, Kroon S, Vadstrup S, Andersen ML, Roy-Poulsen NO. A comparison of 99Tc and 123I scintigraphy in nodular thyroid disor-ders. Eur J Nucl Med 1978; 3(1): 1-4.
  6. Silverberg SJ, Bilezikian JP. Evaluation and management of primary hyperparathyroidism. J Clin Endocrinol Metab 1996; 81(6): 2036-40.
  7. Wermers RA, Khosla S, Atkinson EJ, Achenbach SJ, Oberg AL, Grant CS, et al. Incidence of pri-mary hyperparathyroidism in Rochester, Minne-sota, 1993-2001: an update on the changing ep-idemiology of the disease. J Bone Miner Res 2006; 21(1): 171-7.
  8. Ruda JM, Hollenbeak CS, Stack BC, Jr. A sys-tematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003. Otolaryngol Head Neck Surg 2005; 132(3): 359-72.
  9. Eastell R, Arnold A, Brandi ML, Brown EM, D'Amour P, Hanley DA, et al. Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab 2009; 94(2): 340-50.
  10. Silverberg SJ, Bilezikian JP. "Incipient" primary hyperparathyroidism: a "forme fruste" of an old disease. J Clin Endocrinol Metab 2003; 88(11): 5348-52.
  11. Bilezikian JP, Khan AA, Potts JT, Jr. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the third international workshop. J Clin Endo-crinol Metab 2009; 94(2): 335-9
Journal of Isfahan Medical School
Volume 29, Issue 131 - Serial Number 131
January and February 2011
Pages 266-272

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History

  • Receive Date: 29 April 2011
  • Revise Date: 02 May 2024
  • Accept Date: 06 April 2022

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