Hormonal Receptors Evaluation in Breast Cancer

Document Type : Case Report

Authors

1 Assistant Professor, Department of General Surgery, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Resident, Department of General Surgery, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

Background: Breast cancer is the most common site-specific cancer in women and is of the major leading causes of death from cancer for women aged 20 to 59 years. This study aimed to demonstrate certain biological, clinical and pathological characteristics and to evaluate the breast receptors of patients with this disease.Methods: In this retrospective and descriptive study, 54 patients with breast cancer were selected to participate. All the cases were treated by modified radical mastectomy (MRM). Data was gathered from patients’ records.Finding: The mean age at which breast cancer was first diagnosed, was 50.23 years (Range: 32-75, SD = 11.00 years) and 86.8% of tumors were invasive ductal carcinoma. The mean tumor size was 4.95 cm (Range: 1-11, SD = 2.64 cm). 39 cases were estrogen receptor positive (72.22%) that 19 of them were in patients with right breast tumor. 12 patients (80%) of 15 cases with negative estrogen receptor, had tumor in right breast. In 33 cases which were progesteron receptor positive, 17 had right breast tumor. 14 patients, of 21 cases with negative progesterone receptor, had tumor in right breast.Conclusion: Most of the patients with negative estrogen or progesterone receptor, had tumors in right breast. So, it may be an important proposition in breast cancer world to discover more about it.

Keywords

References

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Journal of Isfahan Medical School
Volume 29, Issue 139 - Serial Number 139
March and April 2011
Pages 621-625

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History

  • Receive Date: 21 November 2010
  • Revise Date: 02 May 2024
  • Accept Date: 06 April 2022

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