Influence of the Anesthetic Depth on the Inhibition of the Oculocardiac Reflex during Propofol Anesthesia for Pediatrics Strabismus Surgery

Document Type : Original Article (s)

Authors

1 Professor, Department of Anesthesia, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Resident, Department of Anesthesia, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: The effect of the anesthetic depth as assessed by bispectral index (BIS) on oculo-cardiac reflex (OCR) during strabismus surgery was controversial. This study was done for determination of Influence of the anesthetic depth on the inhibition of the OCR during propofol anesthesia for pediatrics strabismus surgery.Methods: 75 patients (aged 2-18 years) undergoing strabismus surgery were randomly allocated to one of three groups (25 for each) according to target BIS value of 40, 50 and 60. The propofol concentration was adjusted towards target BIS. The incidence of OCR and the lowest heart rate were recorded in relation to the propofol concentration. The data collected in a check list and then analyzed by χ2 test and one-way ANOVA test by SPSS18.Findings: There is no significant difference between three groups for age and sex (P > 0.05). The incidence of OCR was higher in group with BIS-60 (60%) than in group with BIS-40 (20%) and BIS-50 (28%) (P < 0.001). The propofol concentration was not significantly different between three groups (P > 0.05). Conclusion: We confirme that OCR is relevant to the depth of anaesthesia. It seems that between 40–50 BIS value is adequate for the inhibition of OCR. The results suggest that BIS may be a valuable tool during propofol anaesthesia for strabismus surgery in children.

Keywords

References

  1. Marc AF. Anaesthesia for Eye, Ear, Nose and Throat Surgery. In: Miller RD, editor. Anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2010. p. 2238, 2279.
  2. Reves JG, Glass PS. Travenous Anesthesia. In: Miller RD, editor. Anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2010. p. 726.
  3. Cashman GN. Complications of anaesthesia. In: Rushman GB, Davies NJH, Cashman GN, Lee JA, Atkinson RS, editors. Lee's synopsis of anaesthesia. 12th ed. New York, NY: Butterworth-Heinemann; 1999. p. 265.
  4. Lewandowski KB. Strabismus as a possible sign of subclinical muscular dystrophy predisposing to rhabdomyolysis and myoglobinuria: a study of an affected family. Can Anaesth Soc J 1982; 29(4): 372-6.
  5. Mather SJ, Davy H. Anesthesia for strabismus surgery. Journal of Anaesthesia 2009; 43(11). 1095-9.
  6. Kinouchi K, Okawa M, Fukumitsu K, Tachibana K, Kitamura S, Taniguchi A. Two pediatric cases of malignant hyperthermia caused by sevoflurane. Masui 2001; 50(11): 1232-5. [In Japanese].
  7. Baris S, Karakaya D, Guldogus F, Sarihasan B, Tekat A. A Case of Malignant Hyperthermia During Sevoflurane Anesthesia. Turk J Med Sci 2001; 31(2): 171-3.
  8. Hsu SC, Huang WT, Yeh HM, Hsieh AY. Suspected malignant hyperthermia during sevoflurane anesthesia. J Chin Med Assoc 2007; 70(11): 507-10.
  9. Rosenberg H, Davis M, James D, Pollock N, Stowell K. Malignant hyperthermia. Orphanet J Rare Dis 2007; 2: 21.
  10. Yi C, Jee D. Influence of the anaesthetic depth on the inhibition of the oculocardiac reflex during sevoflurane anaesthesia for paediatric strabismus surgery. Br J Anaesth 2008; 101(2): 234-8.
  11. Henzler D, Kramer R, Steinhorst UH, Piepenbrock S, Rossaint R, Kuhlen R. Factors independently associated with increased risk of pain development after ophthalmic surgery. Eur J Anaesthesiol 2004; 21(2): 101-6.
Journal of Isfahan Medical School
Volume 29, Issue 152 - Serial Number 152
July and August 2011
Pages 1235-1241

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History

  • Receive Date: 18 June 2011
  • Revise Date: 02 May 2024
  • Accept Date: 06 April 2022

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