Association of ABO and Rhesus Blood Groups with Acne Vulgaris

Document Type : Original Article(s)

Authors

1 Associate Professor, Skin and Stem Cell Research Center And Department of Dermatology, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran

2 Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan And Student of Medicine Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran

3 Resident, Department of Dermatology, School of Medicine, Jundishahpour University of Medical sciences, Ahvaz, Iran

Abstract

Background: Acne vulgaris is one of the most common skin disorders worldwide, affecting 85% of adolescents. Acne has significant effects on psychosocial and emotional health particularly in young patients with facial involvement. Much attention has been devoted to find different predisposing factors of acne vulgaris thus far. In this study, we evaluate the association of severe acne vulgaris with ABO and Rh blood groups.Methods: This cross-sectional study recruited 500 consecutive patients with severe acne vulgaris referred to our university hospital dermatology clinic between April 2005 and April 2010. ABO and Rh blood groups of the patients were compared to the previously reported data of 1,300,000 healthy subjects from general population.Findings: Mean age of the patients was 24.11 ± 6.8 years (24.33 ± 6.9 years for women and 22.14 ± 5.0 years for men). Peak age of the disease presentation was 22 in both sexes. Distribution of ABO and Rh blood groups between male and female patients were not significantly different (P = 0.55 and P = 0.33, respectively). ABO blood group distribution among the patients was as follows: blood group O in 44%, A in 25.6%, B in 20.8% and AB in 9.6%. In addition, 92% of patients were Rh positive. When comparing patients with severe acne vulgaris to the control group, there was no statistically significant difference between groups according to ABO/Rh blood groups (P = 0.72 and P = 0.80, respectively). Conclusion: There was no association between ABO/Rh blood groups and the severe form of acne vulgaris. Further studies with greater sample size are recommended for confirming our findings.

Keywords

References

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Journal of Isfahan Medical School
Volume 29, Issue 173 - Serial Number 173
November and December 2012
Pages 3034-3039

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History

  • Receive Date: 12 March 2012
  • Revise Date: 29 April 2024
  • Accept Date: 06 April 2022

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