Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis

Document Type : Original Article (s)

Authors

1 Department of Mechanical Engineering, School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran

2 Assistant Professor, Department of Mechanical Engineering, School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran

Abstract

Background: Diabetes mellitus (DM) is a group of metabolic disorders that lead to hyperglycemia. It also predisposes patients to cardiovascular diseases including atherosclerosis. Atherosclerosis alters the elasticity of arteries. Therefore, changes in elasticity of arteries can be a characteristic of disease progression.Methods: Bulk elasticity of seven individuals with diabetes and a healthy individual was evaluated by measurement of artery diameter during systolic and diastolic phases using Doppler echocardiography and measurement of pulse wave velocity (PWV) using the Sphygmocor system.Findings: Comparing the bulk elasticity evaluated by PWV of the diabetic group with normal ranges in different ages clarified the effects of diabetes on increasing bulk elasticity. The effect of diabetes on bulk elasticity is more obvious as the disease duration increases.Conclusion: PWV can be used as a method to distinguish the characteristics of atherosclerosis.

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References

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Journal of Isfahan Medical School
Volume 29, Issue 174 - Serial Number 174
November and December 2011
Pages 3154-3159

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History

  • Receive Date: 11 August 2011
  • Revise Date: 11 May 2024
  • Accept Date: 06 April 2022

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