1
Department of Mechanical Engineering, School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran
2
Assistant Professor, Department of Mechanical Engineering, School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran
Abstract
Background: Diabetes mellitus (DM) is a group of metabolic disorders that lead to hyperglycemia. It also predisposes patients to cardiovascular diseases including atherosclerosis. Atherosclerosis alters the elasticity of arteries. Therefore, changes in elasticity of arteries can be a characteristic of disease progression.Methods: Bulk elasticity of seven individuals with diabetes and a healthy individual was evaluated by measurement of artery diameter during systolic and diastolic phases using Doppler echocardiography and measurement of pulse wave velocity (PWV) using the Sphygmocor system.Findings: Comparing the bulk elasticity evaluated by PWV of the diabetic group with normal ranges in different ages clarified the effects of diabetes on increasing bulk elasticity. The effect of diabetes on bulk elasticity is more obvious as the disease duration increases.Conclusion: PWV can be used as a method to distinguish the characteristics of atherosclerosis.
Fauci A, Braunwald E, Kasper D, Hauser S, Longo D, Jameson J, et al. Harrison's principles of internal medicine. 2nd ed. London, UK: McGraw-Hill; 2008. p. 338.
Allender S, Scarborough P, Peto V, Raymer M, Leal J, Luengo-Fernandez R, et al. European cardiovascular disease statistics. European Heart Network; 2008. [Online]. Available from: http://www.herzstiftung.ch/uploads/media/European_cardiovascular_disease_statistics_2008.pdf
Blocked right coronary artery. [Figure]. [Online]. Available from: www.ADAM.com.
Peterson LH, Jensen RE, Parnell J. Mechanical properties of arteries in vivo. Circulation Research 1960; 8(3): 622-39.
Boutouyrie P. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: establishing normal and reference values. Eur Heart J 2010; 31(19): 2338-50.
Seyedpour,S. M. , Pachenari,M. and Alizadeh,M. (2012). Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis. Journal of Isfahan Medical School, 29(174), 3154-3159.
MLA
Seyedpour,S. M. , , Pachenari,M. , and Alizadeh,M. . "Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis", Journal of Isfahan Medical School, 29, 174, 2012, 3154-3159.
HARVARD
Seyedpour S. M., Pachenari M., Alizadeh M. (2012). 'Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis', Journal of Isfahan Medical School, 29(174), pp. 3154-3159.
CHICAGO
S. M. Seyedpour, M. Pachenari and M. Alizadeh, "Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis," Journal of Isfahan Medical School, 29 174 (2012): 3154-3159,
VANCOUVER
Seyedpour S. M., Pachenari M., Alizadeh M. Evaluation of Bulk Elasticity to Identify the Effects of Diabetes on Atherosclerosis. JIMS, 2012; 29(174): 3154-3159.