Relations of Disease-Free Survival and Overall Survival with Age and Primary Metastases in Patients with Breast Cancer

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Specialist in Community Medicine, Center for Cancer Prevention and Control in Isfahan Province, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: According to available data, breast cancer occurs about a decade earlier in Iranian women than among the world’s population. This issue magnifies the importance of screening for the disease. Screening will enhance both disease-free survival and overall survival. We assessed the relations of age and primary metastases with disease-free survival and overall survival in patients with breast cancer in Isfahan, Iran.Methods: This retrospective analytic study was conducted during 1998-2009. The study population included women with confirmed breast cancer who had referred to offices of oncologists or Seyed-Al-Shohada Hospital (Isfahan, Iran). Cancer was staged according to the American Joint Committee on Cancer (AJCC) classification. The patients’ information was collected from their files and analyzed.Findings: We followed up patients with breast cancer for over 10 years. The mean age of subjects was 47.9 ± 11.08 years at the time of diagnosis. Disease-free survival was 95 months in patients younger than 40 years of age and 113 months in those above 50 years old. Primary metastases decreased overall survival by 20 months.Conclusion: As expected, the incidence of breast cancer at younger age was found to be associated with decreased disease-free survival and overall survival. As early diagnosis of the disease prevents primary metastases, appropriate screening is of utmost importance.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 225 - Serial Number 225
January and February 2013
Pages 112-120

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History

  • Receive Date: 29 April 2012
  • Revise Date: 05 May 2024
  • Accept Date: 06 April 2022

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