The Effect of Intralesional Triamcinolone versus Combination of Intralesional Triamcinolone with CO2 Fraxel Laser in Treatment of Patients with Hypertrophic Scars

Document Type : Original Article (s)

Authors

1 Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran AND Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Skin Disease and Leishmaniasis Research Center AND Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 General Practitioner, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

4 Student of Medicine, Skin Disease and Leishmaniasis Research Center AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Hypertrophic scars are benign growths of dermal collagen that can couse physical and psychological (cosmetic) problems for patients.Methods: A total of 36 patients were studied and randomly divided into 2 groups; 18 patients were treared with intralesional injection of triamcinolone and 18 other patients were treated with combination of fractional laser and intralesional injection of triamcinolone. The cure rate of the lesions in pain, induration, pruritus, erythema and burning were assessed and compared between the groups.Findings: In group with intralesional injection of triamcinolone, cure rate was 39% in erythema, 45% in pain, 100% in burning, 67% in induration and 45% in pruritus. In group with combination of fractional laser and intralesional injection of triamcinolone, cur was 89% in erythema, 67% in pain, 23% in burning, 83% in induration and 72% in pruritus. The differences between the groups were significant in all issues (P < 0.001 for all).Conclusion: This study showed that combination of fractional laser and intralesional injection of triamcinolone has significantly higher cure rate of hypertrophic scars than intralesional injection of triamcinolone alone.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 233 - Serial Number 233
March and April 2013
Pages 502-509

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History

  • Receive Date: 21 November 2012
  • Revise Date: 28 April 2024
  • Accept Date: 06 April 2022

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