Prevalence of Opportunistic Infections among Hospitalized Patients with HIV/AIDS in Tehran Imam Khomeini Hospital (Iran), during 2009-2012

Document Type : مقاله کوتاه

Authors

1 Professor, Department of Infectious and Tropical Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

2 Associate Professor, Department of Infectious and Tropical Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Specialist in Infectious Diseases, Department of Infectious and Tropical Diseases, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background: Opportunistic infections are the most common cause of hospitalization of patients with HIV/AIDS in developing countries. This study was performed to determine the prevalence of opportunistic infections in hospitalized patients with HIV/AIDS in infectious diseases ward of Tehran Imam Khomeini Hospital (Iran) during 2009-2012.Methods: Patients with HIV/AIDS admitted to infectious diseases ward of Imam Khomeini Hospital were included in the study through census method. Gender variables, CD4 count, history of receiving antiretroviral therapy, cause of admission, length of hospitalization and patients' outcomes were recorded and analyzed.Findings: During the study, 498 patients were included in; 84.3% of whom were men. Opportunistic infections were the most common cause of hospitalization (51.2%) and the most prevalent of which were pulmonary tuberculosis (37.6%), brain toxoplasmosis (18%) and pneumocystis pneumonia (13.3%). Among the patients admitted due to opportunistic infections, 87.5% had CD4 count of less than 200 and 28.6 % had a history of receiving antiretroviral therapy. 54.3% of deceased patients had been admitted due to opportunistic infections.Conclusion: Patients suffering from opportunistic infections had significantly lower CD4 count and longer hospitalization than the others. Widespread application of antiretroviral therapy and the use of new drugs with greater efficacy as well as identification patterns of drug resistance have a dramatic importance to reduce the rate of the opportunistic infections in these patients.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 266 - Serial Number 266
November and December 2014
Pages 2149-2153

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History

  • Receive Date: 17 April 2013
  • Revise Date: 06 May 2024
  • Accept Date: 06 April 2022

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