Assessment of Chromium Levels in Patients with Prediabetes

Document Type : Original Article (s)

Authors

1 General Practitioner, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Department of Internal Medicine, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran

3 General Practitioner, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran

4 Clinical Anatomical Pathologists, School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran

5 Acquired Immune Deficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

6 Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Supplementations of chromium (Cr) have been shown to exert beneficial effects for the management of type-2 diabetes, as reflected by a decline in insulin response. Prevalence of chromium deficiency in patients with prediabetes is not well understood; the aim of this study was to evaluated the amount of this prevalence.Methods: In this cross-sectional descriptive study, were recruited 132 patients with prediabetes. Participants were randomly selected from those referred to the Shariati hospital, Isfahan, Iran. Fasting venous blood samples were collected from participants to measure the levels of chromium, insulin, fasting blood sugar and 2-hour post load plasma glucose. Body mass index was calculated. Determination of Cr was carried out by atomic absorption spectrometry.Findings: Of 132 patients, 24 were excluded due to failure to complete the test. Among remained patients, 34 (31.5%) had chromium deficiency, and 74 (68.5%) had normal serum levels of chromium. A significant inverse relationship was found between chromium levels and age in normal group.Conclusion: Levels of chromium deficiency is relatively common in patients with prediabetes and it is necessary to eliminate chromium deficiency in screening patients for diabetes. 

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 273 - Serial Number 273
January and February 2014
Pages 59-66

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History

  • Receive Date: 26 October 2013
  • Revise Date: 30 April 2024
  • Accept Date: 06 April 2022

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