Prevalence of Herpetic Keratitis in Patients Referred to Feiz Ophthalmology Centre, Isfahan, Iran, Using Polymerase Chain Reaction Method

Document Type : Original Article (s)

Authors

1 General Physician, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate Professor, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Herpes simplex virus 1 (HSV-1) is a major cause of unilateral blindness worldwide. Diagnosis of disease is based on clinical examination. In this study, the prevalence of the virus in patients attending Feiz Ophthalmology Centre, Isfahan, Iran, was determined using polymerase chain reaction (PCR) method.Methods: This descriptive study was done during 2012-2013. 307 samples were taken from patients with clinical keratoconjunctivitis. DNA of HSV-1 was detected using PCR method. The data were evaluated using SPSS software.Findings: From 307 clinical samples, 182 (59.3%) were of women and 125 (40.7%) of men. 20 patients with the mean age of 27.55 ± 3.31 were positive for HSV-1.Conclusion: The prevalence of herpetic keratitis was 6.51%. The frequency is not related to sex.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 278 - Serial Number 278
January and February 2014
Pages 321-329

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History

  • Receive Date: 21 December 2013
  • Revise Date: 29 April 2024
  • Accept Date: 06 April 2022

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