Comparison between Examination with Naked Eye, Curretage and Dermoscopy in Determining Tumor Extension before Mohs Micrographic Surgery

Document Type : Original Article (s)

Authors

1 Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran AND Skin Diseases and Leishmaniasis Research Center AND Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Dermatologist, Skin Diseases and Leishmaniasis Research Center AND Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background: Mohs micrographic surgery (MMS) is a technique for the treatment of cutaneous malignancies. Subtle determination of tumor margin would end to fewer stages of surgery. Our aim was to compare three ways for determining tumor extension before initiation of MMS, examination with the naked eye, dermoscopy and curettage. Methods: Sixty patients with basal cell carcinoma (BCC) in head and neck area were randomized in three groups (curettage, dermoscopy and examination with the naked eye). Each group encompassed twenty patients. The total number of resection stages in MMS was recorded for each patient. Demographic data of the patients and the total number of resection stages in MMS were statistically analyzed. Findings: Based on the results of analysis of variance (ANOVA) test, there was no significant difference for total number of stages between three groups (P = 0.1). The Pearson correlation coefficient showed a direct relation between the age and resection stages (r = 0.19; P = 0.04). The chi‑square test showed no differences between three groups regarding age, residence and radiotherapy history.Conclusion: This study showed that none of the studied methods is better for determining tumor extension before initiation of MMS. Key Words: Curettage, Basal cell carcinoma, Dermoscopy, Mohs micrographic surgery

References

  1. Otley C, Roenigk R. Mohs surgery. In: Bolognia J, Jorizzio J, Rapini R, editors. Bolognia dermatology. 2nd ed. Philadelphia, PA: Mosby; 2008. p. 2274.
  2. Guardiano RA, Grande DJ. A direct comparison of visual inspection, curettage, and epiluminescence microscopy in determining tumor extent before the initial margins are determined for Mohs micrographic surgery. Dermatol Surg 2010; 36(8): 1240-4.
  3. Goldman G. Wound closure materials and instruments. In: Bolognia J, Jorizzio J, Rapini R, editors. Bolognia dermatology. 2nd ed. Philadelphia, PA: Mosby; 2008. p. 2188.
  4. Braun RP, Rabinovitz HS, Oliviero M, Kopf AW, Saurat JH. Dermoscopy of pigmented skin lesions. J Am Acad Dermatol 2005; 52(1): 109-21.
  5. Smith V, Walton S. Treatment of facial Basal cell carcinoma: a review. J Skin Cancer 2011; 2011: 380371.
  6. Pomerantz R, Zell D, McKenzie G, Siegel DM. Optical Coherence Tomography Used as a Modality to Delineate Basal Cell Carcinoma prior to Mohs Micrographic Surgery. Case Rep Dermatol 2011; 3(3): 212-8.
  7. Caresana G, Giardini R. Dermoscopy-guided surgery in basal cell carcinoma. J Eur Acad Dermatol Venereol 2010; 24(12): 1395-9.
  8. Micali G, Lacarrubba F, Massimino D, Schwartz RA. Dermatoscopy: alternative uses in daily clinical practice. J Am Acad Dermatol 2011; 64(6): 1135-46.
  9. Huang CC, Boyce S, Northington M, Desmond R, Soong SJ. Randomized, controlled surgical trial of preoperative tumor curettage of basal cell carcinoma in Mohs micrographic surgery. J Am Acad Dermatol 2004; 51(4): 585-91.
  10. Carducci M, Bozzetti M, De MG, Foscolo AM, Betti R. Usefulness of margin detection by digital dermoscopy in the traditional surgical excision of basal cell carcinomas of the head and neck including infiltrative/morpheaform type. J Dermatol 2012; 39(4): 326-30.
Journal of Isfahan Medical School
Volume 32, Issue 318 - Serial Number 318
November and December 2015
Pages 2360-2366

Files

History

  • Receive Date: 28 June 2014
  • Revise Date: 29 April 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics