The Effect of Vitamin D and Calcium Plus Vitamin D on Sleep Quality in Pregnant Women with Leg Cramps: A Controlled Randomized Clinical Trial

Document Type : Original Article(s)

Authors

1 Assistant Professor, Department of Midwifery, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran

2 Associate Professor, Department of Midwifery, Research Center of Health Effective Social Factors, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran

3 MSc Student, Department of Midwifery, School of Nursing and Midwifery AND Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

4 Associate Professor, Department of Pharmacology, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Background: Evidence indicates that sleep may be affected by using vitamins and minerals or lack of them. This study aimed to determine the effects of vitamin D and calcium-vitamin D in the treatment of sleep disorders in pregnant women with leg cramps.Methods: This triple-blind randomized controlled clinical trial took place on 126 pregnant women referred to Tabriz health centers, Tabriz, Iran, in 2013-2014. Subjects were allocated in to three groups, using block randomization. The groups received vitamin D, calcium-vitamin D and placebo pills daily for 60 days. Sleep score was measured before and after the intervention, using the Pittsburgh Sleep Quality Index. ANCOVA test was used for data analysis.Findings: Controlling baseline score before the intervention, there was no significant differences in the sleep quality score after intervention between the group receiving calcium-vitamin D and the control group (adjusted difference: -0.3, 95% confidence interval: -1.4 to 2.1), the group receiving vitamin D and controls (adjusted difference: -0.007, 95% confidence interval: -1.7 to 1.7) and between the two groups receiving calcium-vitamin D and vitamin D (adjusted difference: -0.3, 95% confidence interval: -1.4 to 2.1). Also, there was no significant difference between the groups in sleep quality subscales (P > 0.05).Conclusion: The results show that calcium-vitamin D and vitamin D does not effect on improving the sleep quality in pregnant women with leg cramps. 

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 320 - Serial Number 320
November and December 2015
Pages 2444-2453

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History

  • Receive Date: 19 March 2015
  • Revise Date: 02 May 2024
  • Accept Date: 06 April 2022

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