Journal of Isfahan Medical School

Journal of Isfahan Medical School

Comparing the Hemodynamic Changes during and after Coronary Artery Bypass Graft Surgery under General Anesthesia with Propofol and Isoflurane

Document Type : Original Article (s)

Authors
Keyvan Bagheri 1
Mohammad Reza Safavi 1
Fahimeh Moheb-Mohammadi 2
1 Associate Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Hemodynamic changes during and after coronary artery bypass graft surgery and the effects of these changes on postoperative complications are important. As there was not any study to compare the effects of propofol and isoflurane on hemodynamic changes during and after coronary artery bypass grafting, we decided to do this.Methods: This clinical trial study was done on 80 patients undergoing coronary artery bypass surgery at the ages of 40 to 70 years in 2014 in Chamran Hospital, Isfahan, Iran. The subjects received isoflurane or propofol in two groups. Hemodynamic changes during coronary artery bypass graft surgery and then every 30 minutes until the end of the surgery and in intensive care unit every two hours to eight hours were compared.Findings: Based on the repeated measure ANOVA test, the differences between the two groups in systolic blood pressure (P = 0.475), diastolic blood pressure (P = 0.885), heart rate (P = 0.130), pulse pressure (P = 0.572) and arterial oxygen saturation (P = 0.425) in 10 times of measuring (before the pumping starts, at pumping, 30, 60, 90 and 120 minutes later, immediately after the pumping and 2, 6 and 8 hours after admission to the intensive care unit) were not significant.Conclusion: In our study, isoflurane and propofol did not cause significant differences in the hemodynamic variables before, during and after coronary artery bypass graft surgery.
Keywords
Propofol
Isoflurane
Coronary Artery Bypass Graft Surgery
Hemodynamic
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Journal of Isfahan Medical School
Volume 33, Issue 342 - Serial Number 342
May and June 2015
Pages 1086-1094

  • Receive Date 22 June 2015
  • Accept Date 06 April 2022