The Frequency of ASC-US, ASC-H, LSIL and HSIL in Pap Smear Tests, Alzahra Hospital, Isfahan, Iran, 2008-2014

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Epidemiologist, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Atypical squamous cells of undetermined significance (ASC-US), atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion (ASC-H), low-grade and high-grade squamous intraepithelial lesion (LSIL and HSIL) are among epithelial cell abnormalities reported on Pap smear test. This study aimed to determine the frequency of ASC-US, ASC-H, LSIL and HSIL on Pap smear reports in the main educational hospital of Isfahan city, Iran.Methods: In this cross-sectional study, reports of ASC-US, ASC-H, LSIL, and HSIL on Pap smear test during 2008 to 2014 were extracted from the pathology archive of Alzahra Hospital. Demographic data of the patients were also extracted from the same archive. Data were analyzed using SPSS software. Descriptive statistics was used to determine the frequency of abnormalities.Findings: We found 46 reports of ASC-US, ASC-H, LSIL, and HSIL among 10754 Pap smear reports in the study time period. Of these, 36 (78.3%), 6 (13%), 3 (6.5%), and 1 (2.2%) were ASC-US, ASC-H, LSIL, and HSIL, respectively. The highest frequency of these epithelial cell abnormalities was reported in 2008 and 2009.Conclusion: Findings of this study show a low frequency of ASC-US, ASC-H, LSIL, and HSIL reports on Pap smear tests in the main educational hospital of Isfahan city. However, these statistics cannot be an exact representative of the frequency of these conditions throughout Isfahan Province. To determine the frequency of these epithelial cell abnormalities on Pap smear tests in Isfahan province, further studies on larger populations are necessary.

Keywords

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Journal of Isfahan Medical School
Volume 33, Issue 353 - Serial Number 353
September and October 2015
Pages 1641-1648

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History

  • Receive Date: 24 December 2014
  • Revise Date: 29 April 2024
  • Accept Date: 06 April 2022

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