Journal of Isfahan Medical School

Journal of Isfahan Medical School

Clinical Manifestations and Radiologic Findings in Adenovirus Respiratory Outbreak in Isfahan Dastgerd Prison, Iran, 2012

Document Type : Original Article (s)

Authors
Alireza Emami-Naeini 1
Behrouz Ataei 1
Majid Yaran 2
Zari Nokhodian 3
Paraisa Shoaei 3
Dana Daneshmand 4
Reza Fadaei-Nobari 5
Abbasali Javadi 6
1 Associate Professor, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Technical Manager, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 PhD Student, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
4 Specialist in Infections Diseases, Hospital Infections Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
5 Specialist in Infections Diseases, Isfahan Province Health Center, Isfahan University of Medical Sciences, Isfahan, Iran
6 Professor, Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Human adenoviruses can cause a wide spectrum of infections including respiratory and ocular disease, gastroenteritis and cystitis. Although adenovirus respiratory infection occurs in children and neonates but several outbreaks of acute respiratory disease (ARD) are documented in military recruits.Methods: In a cross-sectional survey in autumn 2012, all prisoner patients with acute lower respiratory disease referred to Emergency room of Alzahra Hospital, Isfahan, Iran, were enrolled in this study. For diagnosis of the etiology, a panel of different tests was used including PCR (polymerase chain reaction) for respiratory pathogens.Findings: From 23 cases, 21 were positive for adenovirus types in PCR assay of brochoalveolar lavage (BAL). All other Microbiologic tests including Gram staining, culture, and Ziehl-Neelsen staining were negative. The most prevalent radiologic finding in chest X-ray was bilateral interstitial infiltration.Conclusion: Acute respiratory infection by adenovirus may be a cause in respiratory outbreaks in closed environments like prisons and military recruits. PCR is a valuable diagnostic method for early and accurate diagnosis.
Keywords
Adenovirus prison
Respiratory infection
Chest X-ray
Iran
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Journal of Isfahan Medical School
Volume 33, Issue 357 - Serial Number 357
September and October 2016
Pages 1857-1861

  • Receive Date 27 February 2015
  • Accept Date 06 April 2022