Investigation of Mean Platelet Volume among Patients with Sudden Sensorineural Hearing Loss

Document Type : Original Article (s)

Authors

1 Professor, Department of Otolaringology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Department of Otolaringology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

4 Epidemiologist, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Sudden sensorineural hearing loss (SSNHL) refers to the condition in which sudden hearing loss happens and mostly occurs when waking in the morning and is followed by progressive hearing loss within 12 hours or less. SSNHL due to rapid accordance is comorbid to psychological reaction in about 90% of patients. Although SSNHL is idiopathic, some studies show a relation between platelet volume and this disease. The aim of this study was to compare the platelet volume between patients with SSNHL patients and a control group.Methods: In a case control study, during 2012-2013, 55 patients with SSNHL and 55 healthy persons were selected and serum level of mean platelete volume (MPV), wight blood cell (WBC), red blood cell (RBC) and platelet was compared between the two groups.Findings: The mean of MPV in the case and control group was 8.93 ± 0.96 and 9.55 ± 0.99 and the difference between the two groups was statistically significant (P < 0.001). Also, the level of WBC and RBC in case groups was higher than the control groups (P > 0.050).Conclusion: According to the results of this study, the high level of platelet, MPV and hematocrit probably have an effect on SSNHL, which should be mediated. However, another study with a larger sample size is recommended.

Keywords

References

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Journal of Isfahan Medical School
Volume 34, Issue 372 - Serial Number 372
January and February 2016
Pages 120-125

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History

  • Receive Date: 22 July 2015
  • Revise Date: 05 May 2024
  • Accept Date: 06 April 2022

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