Journal of Isfahan Medical School

Journal of Isfahan Medical School

Evaluation and Comparison of Various 3-D Conformal and Intensity-Modulated Radiotherapy Techniques for Treatment of Parotid Gland Cancer

Document Type : Original Article (s)

Authors
Narges Pakseresht 1
Keyvan Jabbari 2
Alireza Amouheidari 3
Mohaddeseh Akbari 1
1 MSc Student, Department of Medical Physics and Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Associate Professor, Department of Medical Physics and Engineering, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Radiation Oncologist, Department of Radiation-Oncology, Isfahan Milad Hospital, Isfahan, Iran
Abstract
Background: In this study, a comparison between various types of radiotherapy treatment for parotid gland cancer was performed to achieve the optimal treatment technique.Methods: Treatment planning and countering performed with TiGRT software for 15 patents with parotid gland cancer. Six techniques were performed and compared. Finally, by comparing the dose volume histograms (DVH), average dose received by each organ was determined and the best method was introduced. Techniques were as: 1. an ipsilateral wedge pair technique using 6 MV photons; 2. a 3-field anteroposterior (AP) (wedged) posteroanterior (PA) (wedged) and lateral portal technique using 6 MV photons; 3. a mixed beam technique using 6 MV photons and 12 MeV electrons (1:4 weighting); 4. a mixed beam technique using 6 MV photons and 15 MeV electrons (1:4 weighting); 5: four 6 MV photon beams with different gantry angles; and 6. similar to fifth technique with an additional small ring around the tumor tissue.Findings: Intensity-modulated arc therapy (IMRT) techniques five and six delivered maximum dose to the target and minimum dose to organ at risks (OAR). Among 3-D conformal radiotherapy techniques (CRT), technique number two delivered more amount of dose to the target than techniques number three and four. The dose delivered to the contrary parotid gland was negligible for intensity-modulated arc therapy techniques.Conclusion: Intensity-modulated arc therapy techniques are most appropriate methods for treating cancer of the parotid gland and the sixth technique delivered better dose distribution in the tumor and healthy tissues. Second D conformal radiotherapy technique delivered higher average dose to the target.
Keywords
Cancer treatment protocols
3-D conformal radiotherapy
Intensity-modulated arc therapy
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Journal of Isfahan Medical School
Volume 35, Issue 417 - Serial Number 417
January and February 2017
Pages 19-25

  • Receive Date 10 November 2016
  • Accept Date 06 April 2022