Evaluating the Relationship between Rheumatic Valvular Heart Disease ‌and Coronary Artery Diseases in Patient with Stable Angina in Isfahan City, Iran

Document Type : Original Article (s)

Authors

1 Resident, Department of Cardiology AND Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Professor, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Assistant Professor, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate Professor, Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Rheumatic heart disease and coronary artery diseases (CAD) are two of main health problems in developing countries. Rheumatic valvular heart disease is less common than coronary artery diseases but it has its importance. This study aimed to evaluate the relationship between rheumatic valvular heart disease and coronary artery diseases in patients with stable angina in Isfahan City, Iran.Methods: This was a case-control study on patients with stable angina who experienced angiography. At first, patients' angiography reports were evaluated and according to them, patients were divided in to two groups including those with or without coronary artery diseases. Then, patient's echocardiography reports were assessed for having valvular heart disease or not special rheumatic valvular heart diseases. Finally, the relationship between having coronary artery diseases and rheumatic valvular heart disease were evaluated.Findings: 1062 patients with mean age of 61.67 ± 11.38 years were evaluated that 64% of them were men. Among participants, 61.3% had coronary artery diseases and 33.9% had rheumatic valvular heart disease that was 12.7% of all valvular heart diseases. About 21.7% of patients with rheumatic valvular heart disease had coronary artery diseases.Conclusion: Patients with rheumatic valvular heart disease showed less prevalence of coronary artery diseases.

Keywords

References

  1. Strategy for controlling rheumatic fever/rheumatic heart disease, with emphasis on primary prevention: memorandum from a joint WHO/ISFC meeting. Bull World Health Organ 1995; 73(5): 583-7.
  2. Marcus RH, Sareli P, Pocock WA, Barlow JB. The spectrum of severe rheumatic mitral valve disease in a developing country. Correlations among clinical presentation, surgical pathologic findings, and hemodynamic sequelae. Ann Intern Med 1994; 120(3): 177-83.
  3. Akhtar N, Sadiq M, Chagani H, Hafeez A, Rizvi FH, Mehboob M. Guidelines for prevention of rheumatic fever and rheumatic heart disease. Pak J Cardiol 2004; 15(3): 136-48.
  4. Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Barwolf C, Levang OW, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J 2003; 24(13): 1231-43.
  5. Levine RA, Hagege AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, et al. Mitral valve disease--morphology and mechanisms. Nat Rev Cardiol 2015; 12(12): 689-710.
  6. Bozbas H, Yildirir A, Kucuk MA, Ozgul A, Atar I, Sezgin A, et al. Prevalence of coronary artery disease in patients undergoing valvular operation due to rheumatic involvement. Anadolu Kardiyol Derg 2004; 4(3): 223-6.
  7. Kruczan DD, Silva NA, Pereira BB, Romao VA, Correa Filho WB, Morales FE. Coronary artery disease in patients with rheumatic and non-rheumatic valvular heart disease treated at a public hospital in Rio de Janeiro. Arq Bras Cardiol 2008; 90(3): 197-203.
  8. Mann D, Zipes D, Libby P, Bonow R. Braunwald's heart disease: A textbook of cardiovascular medicine. 10th ed. Philadelphia, PA: Saunders; 2014. p. 418-9.
  9. Sonmez K, Gencbay M, Akcay A, Yilmaz A, Pala S, Onat O, et al. Prevalence and predictors of significant coronary artery disease in Turkish patients who undergo heart valve surgery. J Heart Valve Dis 2002; 11(3): 431-7.
  10. Ottervanger JP, Thomas K, Sie TH, Haalebos MM, Zijlstra F. Prevalence of coronary atherosclerosis in patients with aortic valve replacement. Neth Heart J 2002; 10(4): 176-80.
  11. Enriquez-Sarano M, Klodas E, Garratt KN, Bailey KR, Tajik AJ, Holmes DR, Jr. Secular trends in coronary atherosclerosis--analysis in patients with valvular regurgitation. N Engl J Med 1996; 335(5): 316-22.
  12. Shaikh AH, Hanif B, Hasan K, Adil A, Hashmani S, Raza M, et al. Coronary artery disease in patients undergoing valve replacement at a tertiary care cardiac centre. J Pak Med Assoc 2011; 61(4): 340-2.
  13. Marchant E, Pichard A, Casanegra P. Report: Association of coronary artery disease and valvular heart disease in chile. Clin Cardiol 1983; 6(7): 352-6.
  14. Rangel A, Hernandez J, Iris JM, Badui E, Chavez E. Indicacion de la coronariografia en las valvulopatias cardiacas. Arch Inst Cardiol Mex 1996; 66(1): 60-9.
  15. Jose VJ, Gupta SN, Joseph G, Chandy ST, George OK, Pati PK, et al. Prevalence of coronary artery disease in patients with rheumatic heart disease in the current era. Indian Heart J 2004; 56(2): 129-31.
Journal of Isfahan Medical School
Volume 35, Issue 455 - Serial Number 455
September and October 2018
Pages 1614-1619

Files

History

  • Receive Date: 26 May 2017
  • Revise Date: 30 April 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics