Journal of Isfahan Medical School

Journal of Isfahan Medical School

Evaluation of Imposed Radiation Dose, Tumor Control Probability (TCP), and Normal Tissue Control Probability (NTCP) for Supraclavicular Nodes Plans of Tangential Method in Radiation Treatment of Patients with Mastectomy

Document Type : Original Article (s)

Authors
Hossein Taheri 1
Mohammad Bagher Tavakoli 2
Ali Akhavan 3
1 MSc Student, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Professor, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Assistant Professor, Department of Radiotherapy Oncology, School of Medicine AND Seyedoshohada Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
10.22122/jims.v36i481.9308
Abstract
Background: The study aimed to evaluate imposed radiation dose and normal tissue complications probability (NTCP) of two common treatment plans of supraclavicular nodes, anterior-posterior (AP) field and parallel opposed fields (POFs) which are widely used in tangential treatment plans for patients with mastectomy.Methods: The stated methods were planned on the computed tomography (CT) scan images of a chest phantom, using TiGRT treatment planning system (TPS). Then, the normal tissue complications probability values were estimated using dose-volume histogram (DVH) data of the plans. According to the plans, the phantom was irradiated with 6 and 15 MV photon beams of a Siemens Primus linac. Dose measurements were also done using thermoluminescence dosimeters.Findings: The mean ± standard deviation (SD) dose to ipsilateral lung (P = 0.045) and heart (P = 0.078) for tangential beams with a single anterior-posterior field (35.42 ± 2.84 and 28.73 ± 3.17 percent, respectively) was significantly lower compared to tangential beams with parallel opposed fields (49.36 ± 2.35 and 30.41 ± 3.77 percent, respectively). In addition, the normal tissue complications probability values of ipsilateral lung and heart for tangential beams with anterior-posterior field (4% and 3%, respectively) was lower compared to tangential with parallel opposed fields (6% and 4%, respectively).Conclusion: It is considered that irradiating supraclavicular nodes with an anterior-posterior field is more suitable technique compared to parallel opposed fields, due to lower imposed dose, and also lower normal tissue complications probability to ipsilateral lung and heart of the patients.
Keywords
Lung
Heart
Mastectomy
Radiation therapy
Lymph nodes
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Journal of Isfahan Medical School
Volume 36, Issue 481 - Serial Number 481
May and June 2018
Pages 564-568

  • Receive Date 05 December 2017
  • Accept Date 06 April 2022