Journal of Isfahan Medical School

Journal of Isfahan Medical School

The Relationship of Blood Groups and in-Hospital Mortality of Patients with Thoracic Aortic Dissection

Document Type : Original Article (s)

Authors
Ahmad Separham 1
Reza Hajizadeh 2
Abdolmohammad Ranjbar 3
Arvin Zabeh 4
Masoumeh Jahanafrouz 4
1 Associate Professor, Department of Cardiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2 Assistant Professor, Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
3 Assistant Professor, Department of Cardiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
4 Student of Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
10.22122/jims.v37i545.11882
Abstract
Background: Acute aortic dissection is one of the catastrophic cardiovascular events with high in-hospital mortality. We aimed to assess the distribution of ABO blood groups in patients with acute aortic dissection, and to identify any association between their blood groups and in-hospital mortality.Methods: In cross-sectional study, 147 patients with confirmed acute aortic dissection by computed tomography angiography were included. According to the type of their blood groups, patients were divided into non-O (including A, B, and AB blood groups) and O blood groups. According to the tearing location, patient were divided into proximal (ascending aorta) and distal (descending aorta) dissection groups. The data were statistically analyzed using chi-square, Fisher's exact, and independent t tests.Findings: The mean age of patients was 58.77 ± 16.04 and 59.3 ± 15.32 years in non-O and O blood groups, respectively. From 147 patients with thoracic aortic dissection, 93 patients had non-O and 54 patients had O blood groups. A and O blood groups were seen more frequently among the patients. 54 patients (36.7%) died during their hospital course. Blood groups of AB [odds ratio (OR) = 3.52] and A (OR = 1.67) had stronger correlation with in-hospital mortality. Patients with blood group O had better in-hospital survival (OR = 0.40).Conclusion: It seems that patients with aortic dissection and O blood group have a better in-hospital survival than patients with non-O blood groups.
Keywords
Aorta
Dissection
Aortic aneurysm
Blood groups
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Journal of Isfahan Medical School
Volume 37, Issue 545 - Serial Number 545
September and October 2019
Pages 1123-1128

  • Receive Date 07 June 2019
  • Accept Date 06 April 2022