Journal of Isfahan Medical School

Journal of Isfahan Medical School

The Effect of 8 Week of Aerobic Exercise on Heart Cells Specific Biochemical Indicators in Women with Type 2 Diabetes Mellitus: A Randomized Clinical Trial

Document Type : Original Article (s)

Authors
Batool Amini-Najafabadi 1
Saeed Keshavarz 2
Sedigheh Asgary 3
Mehrdad Azarbarzin 4
1 PhD Candidate in Sport Physiology, Department of Physical Education and Sports Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran
2 Assistant Professor, Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran
3 Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
4 Assistant Professor, Nursing and Midwifery Sciences Development Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran
10.22122/jims.v38i598.13403
Abstract
Background: The aim of this study was to investigate the effect of aerobic exercise on heart cells specific biochemical indicators in women with type 2 diabetes mellitus.Methods: This randomized clinical trial study was performed on 30 women with type 2 diabetes mellitus randomly divided into experimental and control groups. The experimental group participated in an increasing aerobic exercise (running) for eight weeks, three sessions per week [55% to 75% of maximum heart rate and rating perceived exertion (RPE) of 12 to 13]. Blood samples were taken before and after the protocol. The enzyme-linked immunosorbent assay (ELISA) and enzymatic method were used to measure the variables.Findings: Troponin I decreased significantly 6 hours after the last training session in the experimental group compared to 6 hours after the last training session in the control group (P = 0.001). There was no significant difference in troponin I, 6 hours after the first training session in the experimental group compared to 6 hours after the first training session in the control group (P = 0.983). Creatine kinase-MB (CK-MB) values significantly increased in both groups; this increase was higher in the experimental group than the control group (P = 0.001).Conclusion: The results showed that the training instructions significantly decreased troponin I despite the increase in CPK-MB, which may be due to the nature of training and muscle damage during training. This can confirm the protective nature of this exercise protocol for heart tissue against the injury in women with type 2 diabetes mellitus.
Keywords
Exercise
Troponin I
Creatine Kinase, MB Form
Diabetes mellitus, type 2
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Journal of Isfahan Medical School
Volume 38, Issue 598 - Serial Number 598
September and October 2021
Pages 824-830

  • Receive Date 01 September 2020
  • Accept Date 06 April 2022