The Effect of Intracameral Lidocaine Injection on Hemodynamic Parameters and Pain Intensity during and after Cataract Surgery under Intravenous Sedation and Topical Anesthesia

Document Type : Original Article (s)


1 Assistant Professor, Ophthalmology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Associate Professor, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 Student of Medicine, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


Background: The aim of this study was to evaluate the effect of intracameral lidocaine injection on hemodynamic parameters and pain intensity during and after cataract surgery under intravenous sedation and topical anesthesia.Methods: This clinical trial included 62 patients randomly divided into two groups of 31; the intervention group received intracameral lidocaine with topical tetracaine, and the placebo group received intracameral sterile balance sodium solution (BSS) with topical tetracaine. Baseline and intraoperative and postoperative hemodynamic variables were recorded, and pain intensity were recorded and analyzed upon entering recovery and at different intervals up to 24 hours after the surgery.Findings: Reported pain intensity decreased significantly In both groups over time (P < 0.050). Patients’ pain in the intervention group was significantly lower in comparison to the control group (P < 0.050); but no significant difference was observed between the hemodynamic variables in two groups (P > 0.05)Conclusion: The present study shows that intracameral lidocaine is effective in controlling postoperative pain in patients undergoing cataract surgery without any considerable hemodynamic side effects.


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