Journal of Isfahan Medical School

Journal of Isfahan Medical School

A Review of Pregnancy Outcomes in Pregnant Women Vaccinated Against COVID-19

Document Type : Review Article

Authors
Fereshte Ghahremani 1
Alizadeh leila 1
Marjan Havaei 1
Elnaz Haji Rafiei 1
Seyedeh Maryam Khalili 1
Gity Ozgoly 1
Mahrokh Dolatian 2
1 PhD Student of Reproductive Health, Students Research Committee, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Associate Professor, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
10.48305/jims.v40.i687.0718
Abstract
Background: Evidence has shown that the COVID-19 pandemic can have unpleasant side effects for pregnant women and fetuses. Therefore, vaccination of pregnant women was performed to make this group safe. In order to consolidate the existing knowledge about the effectiveness and consequences of pregnancy in women who underwent this vaccination, this study was designed and implemented.
Methods: In this systematic review study, all published studies up to 24.2.2022 were included in the study. The studies were searched in the databases of Embase, PubMed, Web of Science, Scopus using the keywords Pregnancy, COVID-19 Virus Vaccines, Pregnancy Complications and fetal outcome. The two researchers independently reviewed the articles for quality assessment (using the Newcastle-Ottawa tool) and extracted their main findings.
Findings: In this review study, 10 studies were included in accordance with the inclusion criteria with
40522 pregnant women who received the COVID-19 vaccine. The incidence of maternal complications after vaccination was extremely low. Among pregnant women, there was no significant difference in maternal complications based on whether the vaccine was given in the first, second or third trimester of pregnancy. Covid-19 vaccination during pregnancy was not associated with an increase in pregnancy complications or delivery.
Conclusion: Considering that the safety and efficacy of COVID-19 vaccine are important factors in achieving population immunity, more acceptance of vaccines is essential to achieve adequate immunization coverage. Health care providers can use the available data to educate and empower pregnant women to make informed decisions.
Keywords
Adverse effects
COVID-19 vaccines
Efficiency
Pregnancy outcome
Vaccination
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Journal of Isfahan Medical School
Volume 40, Issue 687
3rd Week, November
November and December 2022
Pages 718-728

  • Receive Date 03 May 1401
  • Accept Date 02 August 1401