The Relationship between the Duration of Onset of Symptoms and the Size of the Intussusception with Successful Placement of the Normal Saline in Children

Document Type : Original Article(s)

Authors

1 Medical Student, Department of Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

2 Assistant Professor, Department of Surgery, School of Medicine, Fatemi Hospital, Ardabil University of Medical Sciences, Ardabil, Iran

3 Associate Professor, Department of Surgery, School of Medicine, Fatemi Hospital, Ardabil University of Medical Sciences, Ardabil, Iran

4 Associate Professor, Department of Community Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

10.48305/jims.v41.i750.1177

Abstract

Background: Intussusception is one of the most common causes of acute abdomen in children. Pediatric surgery centers commonly use barium enemas to treat intussusception. The present study aims to determine the relationship between the time elapsed since the onset of symptoms and the size of intussusception with successful placement with normal saline enema under ultrasound guidance in children.
Methods: The statistical population included all patients referred to Fatemi Ardabil Hospital for treatment from October 2019 to September 2020 with the diagnosis of intussusception. A total of 144 patients were extracted from the HIS system of the hospital. T-test, Square-Chi, and ANOVA tests were used for data analysis, and the logistic regression test was used for multivariate analysis. The p-value values less than 0.05 were considered significant.
Findings: The mean and standard deviation of the age of the participants in the study was 16.8 ± 7.8 months. 80.6% of patients out of 144 patients had successful enemas, and 3.4% had symptoms of disease recurrence. The success rate of normal saline enema was not significantly related to age and gender as well as initial symptoms of the disease. However, the time elapsed since the onset of symptoms and the size of intussusception had a significant relationship.
Conclusion: Attention to the size of intussusception and quick and correct diagnosis of children with it and normal saline enema as an effective treatment method and, barium enema can be useful for treating intussusception in children.

Highlights

Mir Salim Seyedsadeghi: Google Scholar

Iraj Feyzi: Google Scholar

Afshan Sharghi: Google Scholar

Keywords

Main Subjects


  1. Jehangir S, Adams S, Ong T, Wu C, Goetti R, Fowler A, et al. Spinal cord anomalies in children with anorectal malformations: Ultrasound is a good screening test. J Pediatr Surg 2020; 55(7): 1286-91.
  2. Salman R, Sher AC, Sammer MBK, Rodriguez JR, Shah SR, Seghers VJ. Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center. Pediatr Surg Int 2022; 38(3): 437-43.
  3. Singh AP, Tanger R, Mathur V, Gupta AK. Pneumatic reduction of intussusception in children. Saudi Surg J 2017; 5(1): 21-9.
  4. Plut D, Phillips GS, Johnston PR, Lee EY. Practical Imaging Strategies for Intussusception in Children. AJR Am J Roentgenol 2020; 215 (6): 1449-63.
  5. Tang XB, Zhao JY, Bai YZ. Status survey on enema reduction of pediatric intussusception in China. J Int Med Res 2019; 47(2): 859-66.
  6. Sun Z, Song G, Lian D, Zhang Q, Dong L. Process management of intussusception in children: A retrospective analysis in China. Pediatr Emerg Care 2022; 38(7): 321-5.
  7. Talabi AO, Famurewa OC, Bamigbola KT, Sowande OA, Afolabi BI, Adejuyigbe O. Sonographic guided hydrostatic saline enema reduction of childhood intussusception: a prospective study. BMC Emerg Med 2018; 18(1): 46-51.
  8. Rukwong P, Wangviwat N, Phewplung T, Sintusek P. Cohort analysis of pediatric intussusception score to diagnose intussusception. World J Clin Cases 2023; 11(21): 5014-22.
  9. Satter SM, Aliabadi N, Yen C, Gastañaduy PA,
    Ahmed M, Mamun A, et al. Epidemiology of childhood intussusception in Bangladesh: Findings from an active national hospital-based surveillance system, 2012-2016. Vaccine 2018; 36(51): 7805-7810.
  10. Hwang J, Yoon HM, Kim PH, Jung AY, Lee JS, Cho YA. Current diagnosis and image-guided reduction for intussusception in children. Clin Exp Pediatr 2023; 66(1): 12-21.
  11. Trang NV, Burnett E, Ly LH, Anh NP, Hung PH, Linh HM, et al. Recurrent intussusception among infants less than 2 years of age in Vietnam. Vaccine 2018; 36(51): 7901-5.
  12. Prana L, Baijoob S, Rampersad B. Are we doing better? Barium enema reduction of intussusception. Ann R Coll Surg Engl 2018; 100(5): 388-91.
  13. Liu N, Yen C, Huang T, Cui P, Tate JE, Jiang B, et al. Incidence and epidemiology of intussusception among children under 2 years of age in Chenzhou and Kaifeng, China, 2009-2013. Vaccine. 2018; 36(51): 7862-7.
  14. Zhang J, Dong Q, Su X, Long J. Factors associated with in-hospital recurrence of intestinal intussusception in children. BMC Pediatr 2023; 23(1): 428-35.
  15. Zhang B, Wu D, Liu M, Bai J, Chen F, Zhang R, et al. The diagnosis and treatment of retrograde intussusception: a single-centre experience. BMC Surg 2021; 21(1): 398-403.
  16. Tellado MG, Liras J, Mendez R, Somoza I, Sanchez A, Mate A. Ultrasound-guided hydrostatic reduction for the treatment of idiopathic intestinal invagination [in Spanish]. Cir Pediatr 2003; 16(4): 166-8.
  17. Khorana J, Singhavejsakul J, Ukarapol N, Laohapensang M, Wakhanrittee J, Patumanond J. Enema reduction of intussusception: the success rate of hydrostatic and pneumatic reduction. Ther Clin Risk Manag 2015; 11: 1837-42.
  18. Maoate K, Beasley SW. Perforation during gas reduction of intussusception. Pediatr Surg Int 1998; 14(3): 168-75.
  19. Rosenfeld K, McHugh K. Survey of intussusception reduction in England, Scotland and Wales: how and why we could do better. Clin Radiol 1999; 54(7): 452-8.
  20. Daneman A, Alton DJ, Lobo E, Gravett J, Kim P, Ein SH. Patterns of recurrence of intussusception in children: a 17-year review. Pediatr Radiol 1998; 28(12): 913-9.
  21. Chang CY, Chen YY, Lin CH, Sheen JM, Shih WT, Chen KJ, et al. Recurrence of pediatric intussusception: A nationwide population-based descriptive study in Taiwan. Medicine (Baltimore) 2023; 102(35): e34727.
  22. González RD, Pérez-Martínez A, Pisón-Chacón J, Ayuso-González L, Salcedo-Muñoz B, Goñi-Orayen C. Rescue by pneumoenema under general anesthesia of apparently non-reducible intestinal intussusception. Eur J Pediatr 2012; 171(1): 189-91.
  23. Ng E, Kim HB, Lillehei CW, Seefelder C. Life-threatening tension pneumoperitoneum from intestinal perforation during air reduction of intussusception. Paediatr Anaesth 2002; 12(9): 798-800.
  24. Shehata S, El Kholi N, Sultan A, El Sahwi E.
    Hydrostatic reduction of intussusception: barium, air, or saline? Pediatr Surg Int 2000; 16(5-6): 380-6.
  25. Cohen MD. From air to barium and back to air reduction of intussusception in children. Pediatr Radiol 2002; 32(1): 74-80.
  26. Bajaj L, Roback MG. Postreduction management of intussusception in a children’s hospital emergency department. Pediatrics 2003; 112(6): 1302-7.
  27. Stein-Wexler R, O’Connor R, Daldrup-Link H, Wootton-Gorges SL. Current methods for reducing intussusception: survey results. Pediatr Radiol 2015; 45(5): 667-74.
  28. Liu N, Yen C, Huang T, Cui P, Tate JE. Incidence and epidemiology of intussusception among children under 2 years of age in Chenzhou and Kaifeng, China, 2009-2013. Vaccine 2018; 36(51): 7862-7.
  29. Kaiser AD, Applegate KE, Ladd AP. Current success in the treatment of intussusception in children. Surgery 2007; 142(4): 469-77.
  30. Caruso AM, Pane A, Scanu A, Muscas A, Garau R. Intussusception in children: not only surgical treatment. J Pediatr Neonat Individual Med 2017; 6(1): e060135.
  31. Qavami Adel, Al Hossein. The effectiveness of enema with air in the treatment of intussusception in children [in Persian]. Iranian J Child Dis 2018; 15(4): 341-6.‎
  32. Guo WL, Hu ZC, Tan YL, Sheng M, Wang J. Risk factors for recurrent intussusception in children: a retrospective cohort study. BMJ Open 2017; 7(11): e018604.