Document Type : Original Article(s)
Authors
1
Associate Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2
Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3
Medical school, Isfahan university of medical sciences, Isfahan, Iran
10.48305/jims.2024.42145.1670
Abstract
Background: Laparoscopic cholecystectomy has been accepted as a safe and gold standard procedure in the world and has many advantages. However, one of the common complications after laparoscopic cholecystectomy is chronic and sometimes very severe pain. Considering the patients' need to control postoperative pain with drugs that have the least possible side effects, as well as limited studies on the effect of painkillers on pain caused by laparoscopic cholecystectomy, the purpose of this study is to compare the preemptive effect of two drugs. Apotel and ketorolac were used for the first time in patients undergoing laparoscopic cholecystectomy.
Methods: This study was conducted as a three-blind randomized clinical trial on 90 patients aged 18 to 68 years, with ASA class one and two, who underwent general anesthesia for cholecystectomy.
Findings: The findings of this study show that in general, the need for narcotics after cholecystectomy surgery in patients under anesthesia with ketorolac was less than Apotel and the control group. These findings were also confirmed in patients' pain intensity and patients' satisfaction, so that patients' satisfaction in Ketorolac and then Apotel group was higher compared to the control group, which is in line with previous studies in this field.
Conclusion:Therefore, it seems that the overall need for narcotics was lower in ketorolac group than Apotel and lower in Apotel than control.
Highlights
Mohammad Reza Safavi: Google Scholar
Azim Honarmand: Google Scholar, PubMed
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