Journal of Isfahan Medical School

Journal of Isfahan Medical School

Assessing the Impact of Radiation Therapy-Induced Voice Problems on Quality of Life in Non-Laryngeal Head and Neck Cancer Patients

Document Type : Original Article(s)

Authors
Sakineh Bagherzadeh 1
Daryoush Shahbazi-Gahrouei 2
Farhad Torabinezhad 3
1 PhD, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Professor, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Association Professor, Rehabilitation Research Center, Department of Speech & Language Pathology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
10.48305/jims.v42.i791.1002
Abstract
Background: One of the side effects of radiation therapy for non-laryngeal head and neck cancers is laryngeal damage, leading to vocal disorders. Considering the impact of voice on the patient’s quality of life, the long-term follow-up after treatment using a voice handicap index questionnaire is the aim of this study.
Methods: This descriptive-analytical study included 30 patients with non-laryngeal head and neck cancers and 30 normal individuals. Specialized examinations have confirmed damage in the larynx. The VHI Questionnaire sub-group scores were assessed at 6 and 24 months post-treatment, along with the voice quality of patients and a control group at 24 months post-treatment. Pearson's correlation coefficient test was used to assess the relationship between each sub-group of the questionnaire at the two mentioned time points.
Findings: The patients' examination results revealed a significant decrease in the total questionnaire scores from 19.8 at 6 months to 11.37 at 24 months post-treatment (P < 0.05). The study found no significant difference between the patient and control groups after 24 months (P < 0.05). The questionnaire sub-group scores showed a negative correlation, indicating a trend of decreasing scores at the final follow-up.
Conclusion: This study showed that after the treatment, the radiation damage decreased over time and improved the patient's quality of life.

Highlights

Sakineh Bagherzadeh: Google Scholar, PubMed

Keywords
Head and Neck Cancers
VHI questionnaire
Radiotherapy
Life quality
Subjects
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Journal of Isfahan Medical School
Volume 42, Issue 791
3rd Week, January
January and February 2025
Pages 1002-1010

  • Receive Date 08 June 2024
  • Accept Date 11 November 2024